Results 41 to 50 of about 346,127 (305)

Study on the Calcium Transport-Promoting Property and Mechanism of the Peptide–Calcium Complex DEEENDQVK–Ca Based on a Caco-2 Monolayer Model

Foods
Peptide–calcium complexes exhibit promise as calcium supplements due to their enhanced bioavailability. Phosvitin nonapeptide DEEENDQVK (DK) possesses a high calcium-binding capability.
Yaxin Zhang, Jingjing Ru, Shan Gao, Hongli Zhi, Wei Zhao, Chunyan Hao, Xiaowei Zhang   +6 more
doaj   +1 more source

Capsaicin-Induced Ca2+ Influx and Constriction of the Middle Meningeal Artery [PDF]

, 2014
Research in the past on transient receptor potential cation channel subfamily V member 1 (TRPV1) has been limited to mainly nervous tissue TRPV1 because of the channel’s role in pain perception.
Koide, Masayo, Kotlikoff, Michael I., Manuelyan, Inessa, Shui, Bo, Syed, Arsalan U., Wellman, George C.   +5 more
core   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Cortisol modulates calcium release-activated calcium channel gating in fish hepatocytes

Scientific Reports, 2021
Glucocorticoids (GCs) are rapidly released in response to stress and play an important role in the physiological adjustments to re-establish homeostasis.
Chinmayee Das, Manoj K. Rout, Willem C. Wildering, Mathilakath M. Vijayan   +3 more
doaj   +1 more source

Inhibition of synaptic transmission and G protein modulation by synthetic CaV2.2 Ca2+ channel peptides [PDF]

, 2011
: Modulation of presynaptic voltage-dependent Ca+ channels is a major means of controlling neurotransmitter release. The CaV 2.2 Ca2+ channel subunit contains several inhibitory interaction sites for Gβγ subunits, including the amino terminal (NT) and I ...
Agler, Agler, Altier, Bean, Cantí, Catterall, Chaplan, De Waard, De Waard, Dolphin, Drummond, Ertel, Gary J. Stephens, Giovanna Bucci, Herlitze, Herlitze, Herlitze, Hille, Hümmer, Ikeda, Ikeda, Jones, Kajikawa, Lee, Li, Ma, Matthews, Meir, Mochida, Mochida, Mochida, Opatowsky, Page, Page, Page, Qin, Raghib, Richards, Simen, Simen, Stephens, Stephens, Stephens, Stephens, Stephens, Suh, Sumiko Mochida, Tedford, Tedford, Van Petegem, Williams, Yang, Zamponi, Zhang   +53 more
core   +2 more sources

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Inhibition of Contractility of Isolated Caprine Detrusor by the Calcium Channel Blocker Cilnidipine and Reversal by Calcium Channel Openers

Current Therapeutic Research, 2023
: Background: Cilnidipine is a fourth-generation calcium channel blocker that is clinically used to treat hypertension. It is a dihydropyridine that blocks L- and N-type calcium channels.
Steffi A. Maria, MD, Aniket Kumar, PhD, Premila M. Wilfred, MD, Margaret Shanthi, MD, Jacob Peedicayil, MD   +4 more
doaj   +1 more source

Emergence of functional sensory subtypes as defined by transient receptor potential channel expression [PDF]

, 2007
The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
AlQatari, M, Ernfors, P, Hjerling-Leffler, J, Koltzenburg, M   +3 more
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source