Results 1 to 10 of about 503,305 (349)
What calcium channels remember [PDF]
eLife, 2023 A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.
Thomas Kaas +2 more
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Effects of aging on calcium channels in skeletal muscle [PDF]
Frontiers in Molecular BiosciencesIn skeletal muscle, calcium is not only essential to stimulate and sustain their contractions but also for muscle embryogenesis, regeneration, energy production in mitochondria, and fusion.
Mingyi Dong, Andrés Daniel Maturana
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Electrophysiological Mechanisms and Therapeutic Potential of Calcium Channels in Atrial Fibrillation [PDF]
Reviews in Cardiovascular MedicineAtrial fibrillation (AF) is a prevalent and complex arrhythmia for which the pathogenesis involves various electrophysiological factors, notably the regulation of calcium channels.
Zuyuan Huang +3 more
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Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes. [PDF]
Frontiers in Immunology, 2013 In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou +4 more
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Calcium Channels and Calcium-Binding Proteins. [PDF]
Int J Mol Sci, 2023 Signals of nerve impulses are transmitted to excitatory cells to induce the action of organs via the activation of Ca2+ entry through voltage-gated Ca2+ channels (VGCC), which are classified based on their activation threshold into high- and low-voltage activated channels, expressed specifically for each organ [...]
Mochida S.
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The regulation role of calcium channels in mammalian sperm function: a narrative review with a focus on humans and mice [PDF]
PeerJMammalian sperm are characterized as specialized cells, as their transcriptional and translational processes are largely inactive. Emerging researches indicate that Ca2+ serves as a crucial second messenger in the modulation of various sperm ...
Yebin Yang +6 more
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eLife, 2016 The auxiliary α2δ subunits of voltage-gated calcium channels are extracellular membrane-associated proteins, which are post-translationally cleaved into disulfide-linked polypeptides α2 and δ.
Ivan Kadurin +11 more
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Calcium channels as therapeutic targets in head and neck squamous cell carcinoma: current evidence and clinical trials [PDF]
Frontiers in OncologyHead and neck squamous cell carcinoma (HNSCC) originates from the mucosal epithelium of the oral cavity, pharynx, and larynx, and is marked by high rates of recurrence and metastasis.
Jinye Lin +6 more
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Calcium Channels in the Heart: Disease States and Drugs
Cells, 2022 Calcium ions are the major signaling ions in the cells. They regulate muscle contraction, neurotransmitter secretion, cell growth and migration, and the activity of several proteins including enzymes and ion channels and transporters. They participate in
Kajol Shah +4 more
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Frontiers in Physiology, 2022 Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins.
Kunal R. Shah +4 more
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