Results 11 to 20 of about 293,330 (287)

What calcium channels remember [PDF]

open access: yeseLife, 2023
A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.
Thomas Kaas   +2 more
doaj   +2 more sources

Effects of aging on calcium channels in skeletal muscle [PDF]

open access: yesFrontiers in Molecular Biosciences
In skeletal muscle, calcium is not only essential to stimulate and sustain their contractions but also for muscle embryogenesis, regeneration, energy production in mitochondria, and fusion.
Mingyi Dong, Andrés Daniel Maturana
doaj   +2 more sources

The regulation role of calcium channels in mammalian sperm function: a narrative review with a focus on humans and mice [PDF]

open access: yesPeerJ
Mammalian sperm are characterized as specialized cells, as their transcriptional and translational processes are largely inactive. Emerging researches indicate that Ca2+ serves as a crucial second messenger in the modulation of various sperm ...
Yebin Yang   +6 more
doaj   +3 more sources

Calcium Channels and Calcium-Binding Proteins [PDF]

open access: yesInternational Journal of Molecular Sciences, 2023
Signals of nerve impulses are transmitted to excitatory cells to induce the action of organs via the activation of Ca2+ entry through voltage-gated Ca2+ channels (VGCC), which are classified based on their activation threshold into high- and low-voltage activated channels, expressed specifically for each organ [...]
Mochida S.
openaire   +3 more sources

Calcium channels as therapeutic targets in head and neck squamous cell carcinoma: current evidence and clinical trials [PDF]

open access: yesFrontiers in Oncology
Head and neck squamous cell carcinoma (HNSCC) originates from the mucosal epithelium of the oral cavity, pharynx, and larynx, and is marked by high rates of recurrence and metastasis.
Jinye Lin   +6 more
doaj   +2 more sources

Calcium Channels in the Heart: Disease States and Drugs

open access: yesCells, 2022
Calcium ions are the major signaling ions in the cells. They regulate muscle contraction, neurotransmitter secretion, cell growth and migration, and the activity of several proteins including enzymes and ion channels and transporters. They participate in
Kajol Shah   +4 more
doaj   +1 more source

Structural and Functional Coupling of Calcium-Activated BK Channels and Calcium-Permeable Channels Within Nanodomain Signaling Complexes

open access: yesFrontiers in Physiology, 2022
Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins.
Kunal R. Shah   +4 more
doaj   +1 more source

Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique [PDF]

open access: yesE3S Web of Conferences, 2021
As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated ...
Chen Nanjun, Fang Qigeng
doaj   +1 more source

Calcium Permeable Channels in Cancer Hallmarks

open access: yesFrontiers in Pharmacology, 2020
Cancer, the second cause of death worldwide, is characterized by several common criteria, known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death resistance, angiogenesis, invasion and metastasis.
Sendoa Tajada, Carlos Villalobos
doaj   +1 more source

Calcium Channels: Noteworthy Regulators and Therapeutic Targets in Dermatological Diseases

open access: yesFrontiers in Pharmacology, 2021
Dysfunctional skin barrier and impaired skin homeostasis may lead to or aggravate a series of dermatologic diseases. A large variety of biological events and bioactive molecules are involved in the process of skin wound healing and functional recovery ...
Min Wang   +6 more
doaj   +1 more source

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