What calcium channels remember [PDF]
eLife, 2023 A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.
Thomas Kaas +2 more
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Calcium Channels in the Heart: Disease States and Drugs
Cells, 2022 Calcium ions are the major signaling ions in the cells. They regulate muscle contraction, neurotransmitter secretion, cell growth and migration, and the activity of several proteins including enzymes and ion channels and transporters. They participate in
Kajol Shah +4 more
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Calcium Permeable Channels in Cancer Hallmarks
Frontiers in Pharmacology, 2020 Cancer, the second cause of death worldwide, is characterized by several common criteria, known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death resistance, angiogenesis, invasion and metastasis.
Sendoa Tajada, Carlos Villalobos
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Effects of aging on calcium channels in skeletal muscle [PDF]
Frontiers in Molecular BiosciencesIn skeletal muscle, calcium is not only essential to stimulate and sustain their contractions but also for muscle embryogenesis, regeneration, energy production in mitochondria, and fusion.
Mingyi Dong, Andrés Daniel Maturana
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Host Calcium Channels and Pumps in Viral Infections
Cells, 2019 Ca2+ is essential for virus entry, viral gene replication, virion maturation, and release. The alteration of host cells Ca2+ homeostasis is one of the strategies that viruses use to modulate host cells signal transduction mechanisms in their favor.
Xingjuan Chen, Ruiyuan Cao, Wu Zhong
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Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes. [PDF]
Frontiers in Immunology, 2013 In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou +4 more
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Electrophysiological Mechanisms and Therapeutic Potential of Calcium Channels in Atrial Fibrillation [PDF]
Reviews in Cardiovascular MedicineAtrial fibrillation (AF) is a prevalent and complex arrhythmia for which the pathogenesis involves various electrophysiological factors, notably the regulation of calcium channels.
Zuyuan Huang +3 more
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Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology [PDF]
Journal of Physiology, 2016 Voltage-gated calcium channels are essential players in many physiological processes in excitable cells. There are three main subdivisions of calcium channel, defined by the pore-forming α1 subunit, the CaV 1, CaV 2 and CaV 3 channels.
Dolphin, AC
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The roles of the subunits in the function of the calcium channel [PDF]
, 1991 Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha ...
Biel, Martin +5 more
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The regulation role of calcium channels in mammalian sperm function: a narrative review with a focus on humans and mice [PDF]
PeerJMammalian sperm are characterized as specialized cells, as their transcriptional and translational processes are largely inactive. Emerging researches indicate that Ca2+ serves as a crucial second messenger in the modulation of various sperm ...
Yebin Yang +6 more
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