Results 21 to 30 of about 3,253,102 (352)

Presynaptic calcium channels [PDF]

open access: yesNeuroscience Research, 2018
Presynaptic Ca2+ entry occurs through voltage-gated Ca2+ (CaV) channels which are activated by membrane depolarization. Depolarization accompanies neuronal firing and elevation of Ca2+ triggers neurotransmitter release from synaptic vesicles. For synchronization of efficient neurotransmitter release, synaptic vesicles are targeted by presynaptic Ca2 ...
openaire   +4 more sources

Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion

open access: yesFrontiers in Endocrinology, 2017
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration.
Stanko S. Stojilkovic   +2 more
doaj   +1 more source

Intercommunication between Voltage-Gated Calcium Channels and Estrogen Receptor/Estrogen Signaling: Insights into Physiological and Pathological Conditions

open access: yesCells, 2022
Voltage-gated calcium channels (VGCCs) and estrogen receptors are important cellular proteins that have been shown to interact with each other across varied cells and tissues.
Yashashwini Dinesh Subbamanda   +1 more
doaj   +1 more source

Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC

open access: yesMolecular Brain, 2019
This study describes the functional interaction between Cav3.2 calcium channels and the Epithelial Sodium Channel (ENaC). β-ENaC subunits showed overlapping expression with endogenous Cav3.2 calcium channels in the thalamus and hypothalamus as detected ...
Agustin Garcia-Caballero   +7 more
doaj   +1 more source

Presynaptic Calcium Channel Open Probability and Changes in Calcium Influx Throughout the Action Potential Determined Using AP-Waveforms

open access: yesFrontiers in Synaptic Neuroscience, 2020
Action potentials arriving at a nerve terminal activate voltage-gated calcium channels and set the electrical driving force for calcium entry which affects the amount and duration of neurotransmitter release.
Matthew S. Scarnati   +6 more
doaj   +1 more source

Voltage‐gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology

open access: yesJournal of Physiology, 2016
Voltage‐gated calcium channels are essential players in many physiological processes in excitable cells. There are three main subdivisions of calcium channel, defined by the pore‐forming α1 subunit, the CaV1, CaV2 and CaV3 channels.
A. Dolphin
semanticscholar   +1 more source

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling

open access: yesNature Communications, 2016
Mounting in vitro, in vivo and clinical evidence suggest an important role for filopodia in driving cancer cell invasion. Using a high-throughput microscopic-based drug screen, we identify FDA-approved calcium channel blockers (CCBs) as potent inhibitors
Guillaume Jacquemet   +10 more
semanticscholar   +1 more source

Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification

open access: yesNature Communications, 2022
Ultrasonic neuromodulation has the unique potential to provide non-invasive control of neural activity in deep brain regions with high spatial precision and without chemical or genetic modification.
Sangjin Yoo   +4 more
semanticscholar   +1 more source

Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes.

open access: yesFrontiers in Immunology, 2013
In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou   +4 more
doaj   +1 more source

SLO BK Potassium Channels Couple Gap Junctions to Inhibition of Calcium Signaling in Olfactory Neuron Diversification. [PDF]

open access: yesPLoS Genetics, 2016
The C. elegans AWC olfactory neuron pair communicates to specify asymmetric subtypes AWCOFF and AWCON in a stochastic manner. Intercellular communication between AWC and other neurons in a transient NSY-5 gap junction network antagonizes voltage ...
Amel Alqadah   +8 more
doaj   +1 more source

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