Results 21 to 30 of about 3,593,980 (394)
Physiology, 2017 In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on ...
M. Trebak, J. Putney
semanticscholar +3 more sources
Calcium channels as therapeutic targets in head and neck squamous cell carcinoma: current evidence and clinical trials [PDF]
Frontiers in OncologyHead and neck squamous cell carcinoma (HNSCC) originates from the mucosal epithelium of the oral cavity, pharynx, and larynx, and is marked by high rates of recurrence and metastasis.
Jinye Lin +6 more
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Frontiers in Physiology, 2022 Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins.
Kunal R. Shah +4 more
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Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique [PDF]
E3S Web of Conferences, 2021 As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated ...
Chen Nanjun, Fang Qigeng
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Calcium Channels: Noteworthy Regulators and Therapeutic Targets in Dermatological Diseases
Frontiers in Pharmacology, 2021 Dysfunctional skin barrier and impaired skin homeostasis may lead to or aggravate a series of dermatologic diseases. A large variety of biological events and bioactive molecules are involved in the process of skin wound healing and functional recovery ...
Min Wang +6 more
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Calcium Channels and Calcium-Binding Proteins. [PDF]
Int J Mol Sci, 2023 Signals of nerve impulses are transmitted to excitatory cells to induce the action of organs via the activation of Ca2+ entry through voltage-gated Ca2+ channels (VGCC), which are classified based on their activation threshold into high- and low-voltage activated channels, expressed specifically for each organ [...]
Mochida S.
europepmc +3 more sources
Regulation of Presynaptic Calcium Channels by Synaptic Proteins
Journal of Pharmacological Sciences, 2003 Calcium entry into nerve termini via voltage gated calcium channels is an essential step in neurotransmission. Consequently, second messenger regulation of calcium channel activity modulates synaptic activity.
Gerald W. Zamponi
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The involvement of TRP channels in bone homeostasis
Frontiers in Endocrinology, 2012 Calcium and bone homeostasis are intimately related. On the one hand, bone relies on a sufficient supply of calcium to maintain its structural and mechanical properties and thus largely depends on calcium absorption in the intestine and calcium ...
Liesbet eLieben, Geert eCarmeliet
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MODULATION OF THE CGMP-GATED CHANNEL BY CALCIUM [PDF]
, 1995 Calcium acting through calmodulin has been shown to regulate the affinity of cyclic nucleotide-gated channels expressed in cell lines.
LAGNADO, L, SAGOO, MS
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Vacuolar calcium channels [PDF]
Journal of Experimental Botany, 2007 The central vacuole is the largest Ca2+ store in a mature plant cell. Ca2+ release from this store contributes to Ca2+-mediated intracellular signalling in a variety of physiological responses. However, the routes for vacuolar Ca2+ release are not well characterized.
I I, Pottosin, G, Schönknecht
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