Results 31 to 40 of about 3,593,980 (394)

Presynaptic calcium channels [PDF]

open access: yesNeuroscience Research, 2018
Presynaptic Ca2+ entry occurs through voltage-gated Ca2+ (CaV) channels which are activated by membrane depolarization. Depolarization accompanies neuronal firing and elevation of Ca2+ triggers neurotransmitter release from synaptic vesicles. For synchronization of efficient neurotransmitter release, synaptic vesicles are targeted by presynaptic Ca2 ...
openaire   +3 more sources

Calcium channel gating [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2018
Tuned calcium entry through voltage-gated calcium channels is a key requirement for many cellular functions. This is ensured by channel gates which open during membrane depolarizations and seal the pore at rest. The gating process is determined by distinct sub-processes: movement of voltage-sensing domains (charged S4 segments) as well as opening and ...
Hering, S.   +5 more
openaire   +2 more sources

Intercommunication between Voltage-Gated Calcium Channels and Estrogen Receptor/Estrogen Signaling: Insights into Physiological and Pathological Conditions

open access: yesCells, 2022
Voltage-gated calcium channels (VGCCs) and estrogen receptors are important cellular proteins that have been shown to interact with each other across varied cells and tissues.
Yashashwini Dinesh Subbamanda   +1 more
doaj   +1 more source

Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]

open access: yes, 1990
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S.   +3 more
core   +1 more source

Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion

open access: yesFrontiers in Endocrinology, 2017
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration.
Stanko S. Stojilkovic   +2 more
doaj   +1 more source

Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels

open access: yesFrontiers in Physiology, 2020
Transient receptor potential canonical 6 (TRPC6) channels are non-selective cation channels that are thought to underlie mechano-modulation of calcium signaling in cardiomyocytes.
Azmi A. Ahmad   +6 more
doaj   +1 more source

Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart [PDF]

open access: yes, 2015
With aging, there is a decline in cardiac function accompanying increasing risk of arrhythmias. These effects are likely to be mechanistically associated with age-associated changes in calcium regulation within cardiac myocytes.
Close, Graeme L.   +6 more
core   +2 more sources

Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC

open access: yesMolecular Brain, 2019
This study describes the functional interaction between Cav3.2 calcium channels and the Epithelial Sodium Channel (ENaC). β-ENaC subunits showed overlapping expression with endogenous Cav3.2 calcium channels in the thalamus and hypothalamus as detected ...
Agustin Garcia-Caballero   +7 more
doaj   +1 more source

Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]

open access: yes, 2016
© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L.   +3 more
core   +2 more sources

Presynaptic Calcium Channel Open Probability and Changes in Calcium Influx Throughout the Action Potential Determined Using AP-Waveforms

open access: yesFrontiers in Synaptic Neuroscience, 2020
Action potentials arriving at a nerve terminal activate voltage-gated calcium channels and set the electrical driving force for calcium entry which affects the amount and duration of neurotransmitter release.
Matthew S. Scarnati   +6 more
doaj   +1 more source

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