SLO BK Potassium Channels Couple Gap Junctions to Inhibition of Calcium Signaling in Olfactory Neuron Diversification. [PDF]
PLoS Genetics, 2016 The C. elegans AWC olfactory neuron pair communicates to specify asymmetric subtypes AWCOFF and AWCON in a stochastic manner. Intercellular communication between AWC and other neurons in a transient NSY-5 gap junction network antagonizes voltage ...
Amel Alqadah +8 more
doaj +1 more source
Particle-based Multiscale Modeling of Calcium Puff Dynamics [PDF]
Multiscale Model. Simul. 14, 997-1016 (2016), 2015 Intracellular calcium is regulated in part by the release of Ca$^{2+}$ ions from the endoplasmic reticulum via inositol-4,5-triphosphate receptor (IP$_3$R) channels (among other possibilities such as RyR and L-type calcium channels). The resulting dynamics are highly diverse, lead to local calcium "puffs" as well as global waves propagating through ...
arxiv +1 more source
T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis
Frontiers in Endocrinology, 2016 Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier +1 more
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Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. [PDF]
PLoS ONE, 2013 Calcium-activated potassium channels of the KCa1.1 class are known to regulate repolarization of action potential discharge through a molecular association with high voltage-activated calcium channels.
Renata Rehak +5 more
doaj +1 more source
CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
eLife, 2023 Activation of voltage-gated calcium channels at presynaptic terminals leads to local increases in calcium and the fusion of synaptic vesicles containing neurotransmitter.
Brian D Mueller +12 more
doaj +1 more source
Energetics of discrete selectivity bands and mutation-induced transitions in the calcium-sodium ion channels family [PDF]
Phys. Rev. E 88, 052712 (2013), 2013 We use Brownian dynamics simulations to study the permeation properties of a generic electrostatic model of a biological ion channel as a function of the fixed charge $Q_f$ at its selectivity filter. We reconcile the recently-discovered discrete calcium conduction bands M0 ($Q_f$=1e), M1 (3e), M2 (5e) with the set of sodium conduction bands L0 (0.5-0 ...
arxiv +1 more source
Membrane Currents in Airway Smooth Muscle: Mechanisms and Therapeutic Implications
Canadian Respiratory Journal, 1997 Electrophysiological and pharmacological techniques were used to characterize the membrane conductance changes underlying spasmogen-evoked depolarization in airway smooth muscle (ASM).
Luke J Janssen
doaj +1 more source
Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes.
Frontiers in Immunology, 2013 In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou +4 more
doaj +1 more source
Store-operated calcium channels in skin
Frontiers in Physiology, 2022 The skin is a complex organ that acts as a protective layer against the external environment. It protects the internal tissues from harmful agents, dehydration, ultraviolet radiation and physical injury as well as conferring thermoregulatory control ...
Declan Manning +3 more
doaj +1 more source
CavĪ² surface charged residues contribute to the regulation of neuronal calcium channels
Molecular Brain, 2022 Voltage-gated calcium channels are essential regulators of brain function where they support depolarization-induced calcium entry into neurons. They consist of a pore-forming subunit (CavĪ±1) that requires co-assembly with ancillary subunits to ensure ...
Alexandra Tran-Van-Minh +2 more
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