Results 31 to 40 of about 542,671 (376)
MODULATION OF THE CGMP-GATED CHANNEL BY CALCIUM [PDF]
, 1995 Calcium acting through calmodulin has been shown to regulate the affinity of cyclic nucleotide-gated channels expressed in cell lines.
LAGNADO, L, SAGOO, MS
core +1 more source
Frontiers in Cellular Neuroscience, 2019 Voltage-gated ion channels are essential for signal generation and propagation in neurons and other excitable cells. The high-voltage activated calcium-channel Cav2.3 is expressed throughout the central and peripheral nervous system, and within CA1 ...
Jakob J. Gutzmann +2 more
doaj +1 more source
Particle-based Multiscale Modeling of Calcium Puff Dynamics [PDF]
Multiscale Model. Simul. 14, 997-1016 (2016), 2015 Intracellular calcium is regulated in part by the release of Ca$^{2+}$ ions from the endoplasmic reticulum via inositol-4,5-triphosphate receptor (IP$_3$R) channels (among other possibilities such as RyR and L-type calcium channels). The resulting dynamics are highly diverse, lead to local calcium "puffs" as well as global waves propagating through ...
arxiv +1 more source
Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]
, 1990 In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S. +3 more
core +1 more source
Activation of Calcium Channels
Biophysical Journal, 1984 Activation of Ca channels has been described as a Hodgkin-Huxley process in which the time constants have ratios of two or greater (1, 2, 3) or as a three-state linear sequential process with two very different time constants (4). We examined activation by measuring the turn-on and turn-off of macroscopic Ca currents and the discharge of single Ca ...
Arthur Brown +2 more
openaire +3 more sources
Mitogens and Calcium Channels [PDF]
Physiology, 1997 Mitogens and, in particular, growth factors can induce changes in free intracellular Ca2+ concentration by opening voltage-independent cationic channels, with different degrees of Ca2+ selectivity. Recent work has provided preliminary insights into the nature of these channels and their role in the control of cell cycle progression.
LOVISOLO, Davide +3 more
openaire +3 more sources
Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. [PDF]
PLoS ONE, 2013 Calcium-activated potassium channels of the KCa1.1 class are known to regulate repolarization of action potential discharge through a molecular association with high voltage-activated calcium channels.
Renata Rehak +5 more
doaj +1 more source
Store-operated calcium channels in skin
Frontiers in Physiology, 2022 The skin is a complex organ that acts as a protective layer against the external environment. It protects the internal tissues from harmful agents, dehydration, ultraviolet radiation and physical injury as well as conferring thermoregulatory control ...
Declan Manning +3 more
doaj +1 more source
Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart [PDF]
, 2015 With aging, there is a decline in cardiac function accompanying increasing risk of arrhythmias. These effects are likely to be mechanistically associated with age-associated changes in calcium regulation within cardiac myocytes.
Close, Graeme L. +6 more
core +2 more sources
Medicine, 2003 Overdose of calcium channel blockers is potentially lethal. Verapamil and diltiazem are much more dangerous than dihydropyridines. Hypotension with (verapamil and diltiazem) or without (dihydropyridines) heart block and bradycardia are the most important features.
Ian M Whyte +5 more
openaire +3 more sources