Results 121 to 130 of about 652,107 (224)

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Endoscopic calcium electroporation in patients with precancerous cellular changes in the esophagus

European Journal of Surgical Oncology
Barrett's esophagus high-grade dysplasia (BE HGD) can transform into esophageal adenocarcinoma (EAC) in 19-28 % of the cases. Calcium electroporation (Ca-EP) is a novel anti-cancer therapy where electrical pulses are combined with a local injection of calcium to increase intracellular calcium levels leading to cell death.
Laser Arif Bazancir, Charlotte Egeland, Rajendra Singh Garbyal, Julie Gehl, Michael Patrick Achiam   +4 more
openaire   +3 more sources

A Rapid Lithium Ion‐Based Transformation Method for Kluyveromyces lactis

Yeast, EarlyView.
ABSTRACT Kluyveromyces lactis is a budding yeast host useful for recombinant protein production; however, its transformation often relies on electroporation due to the perceived low efficiency of chemical methods, thereby limiting throughput. In this study, we developed a robust, small‐scale chemical transformation protocol (using 15 μL of competent ...
Daisuke Tsugama, Ziyi Zuo
wiley   +1 more source

The bystander effect after electroporation with microsecond and nanosecond pulses

Anti-cancer treatment by electrochemotherapy is based on the phenomenon of electroporation, where tumor tissue cells are exposed to highintensity, short external electric fields. When the transmembrane potential exceeds a critical value, cytotoxic drugs (
Barauskaitė-Šarkinienė, Neringa, Borinskytė, Ugnė, Novickij, Vitalij, Ruzgys, Paulius, Šatkauskas, Saulius   +4 more
core  

Dye Electroporation and Imaging of Calcium Signaling in Xenopus Nervous System

, 2018
Electroporation is an efficient method of transferring charged macromolecules into living cells in order to study their morphology, function, and connectivity within neuronal networks. Labeling cells with fluorophore-coupled macromolecules can be used to trace projections of whole neuronal ensembles, as well as the fine morphology of single cells. Here,
Weiss, Lukas, Offner, Thomas, Hassenklöver, Thomas, Manzini, Ivan, Vleminckx, Kris   +4 more
openaire   +3 more sources

Factors influencing electroporation-mediated gene transfer to Stylosanthes guianensis (Aubl.) Sw. protoplasts

Genetics and Molecular Biology, 2002
In order to develop a high-efficiency and reproducible transformation protocol for Stylosanthes guianensis we assessed the biological and physical parameters affecting plant electroporation protoplasts.
Quecini V.M., Oliveira C.A. de, Alves A.C., Vieira M.L.C.   +3 more
doaj  

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

Calcium Electroporation Reduces Viability and Proliferation Capacity of Four Uveal Melanoma Cell Lines in 2D and 3D Cultures. [PDF]

Cancers (Basel), 2022
Kraemer MM, Tsimpaki T, Berchner-Pfannschmidt U, Bechrakis NE, Seitz B, Fiorentzis M.   +5 more
europepmc   +1 more source

The PART randomised trial protocol: Partial Ablation versus Radical Treatment for prostate cancer

BJU International, EarlyView.
Objectives Primary objective: to determine whether prostate gland partial ablation (PA) has non‐inferior oncological treatment success vs radical treatment (RT) of localised intermediate‐risk prostate cancer (irPCa). Secondary objectives: to compare (i) participant‐reported urinary and sexual dysfunction side effects, (ii) short/medium term serious ...
Richard J. Bryant, Tom Leslie, Marc Laniado, Abhishek Sharma, Alistair Grey, John Withington, Christopher Blick, Edward Streeter, Sanjeev Kotwal, Oliver Hulson, William Cross, Daniel W. Good, Altan Omer, Taimur T. Shah, Nishant Bedi, Luke Stroman, Caroline Moore, Prasanna Sooriakumaran, Hashim U. Ahmed, Simon F. Brewster, Vicki S. Barber, Aimi Hewitt, Clare Calvert, Jessica Scaife, Derek Shepherd, Filipa Landeiro, Jane Wolstenholme, Philip Camilleri, Clare Verrill, Shelagh Lovell, Martin Pirkl, Fergus Gleeson, Roxanne Williams, Jo Cook, Catherine R. Holt, Martyn Hill, Jonathan Cook, James Radford, Ioana R. Marian, Ruth Macpherson, Daisy Elliott, Jenny L. Donovan, Freddie C. Hamdy   +42 more
wiley   +1 more source

Transurethral ultrasound ablation (TULSA) for prostate cancer: a systematic review and meta‐analysis

BJU International, EarlyView.
Objective Our objective was to synthesise evidence on oncological, functional and safety outcomes of magnetic resonance imaging‐guided transurethral ultrasound ablation (TULSA) for primary and recurrent prostate cancer. Methods MEDLINE, Embase, Web of Science and Scopus were systematically searched from inception to July 2025. The primary outcomes were
Eugene Wang, Xinyi Wei, Yajat Dua, Marlon Perera, Jeremy Grummet   +4 more
wiley   +1 more source