Results 181 to 190 of about 1,971,191 (306)

Mitochondrial Calcium Signaling in Hepatocyte Health and Disease. [PDF]

Cold Spring Harb Perspect Biol
Eberhardt DR, Chaudhuri D.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

IP3R2-mediated inter-organelle calcium signaling suppresses melanosome degradation. [PDF]

PLoS Biol
Saurav S, Jadon A, Motiani RK.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Editorial: Adenine nucleotides in immunity and inflammation

Frontiers in Immunology
Christa E. Müller, Santina Bruzzone, Andreas H. Guse   +2 more
doaj   +1 more source

Calcium Signaling in Macrophages During a Wound Response In Vivo. [PDF]

Int J Mol Sci
Munos JA, Lam PY.
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Calcium signaling in human and mouse microglia exhibit differential susceptibility to phytocannabinoids. [PDF]

Cell Commun Signal
Pilchova I, Fleig A, Penner R.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Refractory Behavior in Plant Cells-Calcium Signaling Induced by Biotic Stress. [PDF]

Plants (Basel)
Keßler MK, Fulek V, Niehaus K, Lutter P.   +3 more
europepmc   +1 more source