Results 161 to 170 of about 770,691 (293)

Rules of life at the interface of calcium signaling and mechanobiology. [PDF]

APL Bioeng
Li L, Gazzo D, Saad SM, Larson NJ, Kim ES, Kumar N, Mim MS, Krishnan MJ, Speybroeck B, Ding C, Xiao S, Mullins MC, Iyer-Pascuzzi AS, Deng Q, Pienaar E, Evans JP, Umulis DM, Zartman JJ.   +17 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Nootkatone antifungal activity and calcium signaling-mediated resistance in Aspergillus fumigatus. [PDF]

Appl Microbiol Biotechnol
Xu J, Song L, Chen Y, Tang J, Lv X, Du H, Song J, Tian J.   +7 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Editorial: Adenine nucleotides in immunity and inflammation

Frontiers in Immunology
Christa E. Müller, Santina Bruzzone, Andreas H. Guse   +2 more
doaj   +1 more source

Pyrimidinergic calcium signaling links tubular metabolism to fibrosis in kidney disease. [PDF]

Nat Commun
Figurek A, Jankovic N, Kollar S, Kaminska M, Sakhi I, Rinaldi A, Cippà PE, Robaye B, Hall AM.   +8 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

TSC-associated microglial hyperactivity: enhanced calcium signaling, metabolism, and phagocytosis. [PDF]

Acta Neuropathol
Kalf RS, Luinenburg MJ, Dematteis G, Scheper M, Anink JJ, Cavallo G, Mattarei A, Van Hecke W, Mühlebner A, Tapella L, Mills JD, Lim D, Aronica E.   +12 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Endocrine Disorders of Calcium Signaling in Children: Neuroendocrine Crosstalk and Clinical Implications. [PDF]

Cells
Paparella R, Pastore F, Marchetti L, Bei A, Bernabei I, Iafrate N, Maglione V, Niceta M, Zambrano A, Celli M, Fiore M, Pucarelli I, Tarani L.   +12 more
europepmc   +1 more source