Results 11 to 20 of about 777,357 (346)

Genetically Encoded Calcium Indicators: A New Tool in Renal Hypertension Research [PDF]

Frontiers in Medicine, 2019
Hypertension is ranked as the third cause of disability-adjusted life-years. The percentage of the population suffering from hypertension will continue to increase over the next years.
Cheng Zhong, Johanna Schleifenbaum
doaj   +3 more sources

Orai and TRPC channel characterization in FcεRI‐mediated calcium signaling and mediator secretion in human mast cells [PDF]

, 2017
Inappropriate activation of mast cells via the FcεRI receptor leads to the release of inflammatory mediators and symptoms of allergic disease. Calcium influx is a critical regulator of mast cell signaling and is required for exocytosis of preformed ...
Hannah Wajdner, Jasmine Farrington, Claire Barnard, Peter T. Peachell, Christine G. Schnackenberg, Joseph P. Marino, Xiaoping Xu, Karen Affleck, Malcolm Begg, Elizabeth P. Seward   +9 more
openalex   +4 more sources

Information transfer in signaling pathways : a study using coupled simulated and experimental data [PDF]

, 2008
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown.
Pahle, Jürgen, Green, Anne K., Dixon, C. Jane, Kummer, U. (Ursula)   +3 more
core   +7 more sources

Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia

Frontiers in Cell and Developmental Biology, 2020
In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions.
Shunhui Wei, See Wee Low, Charlene Priscilla Poore, Bo Chen, Yahui Gao, Bernd Nilius, Ping Liao, Ping Liao, Ping Liao   +8 more
doaj   +1 more source

NAADP Signaling: New Kids on the Block

Cells, 2022
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of ...
Andreas H. Guse
doaj   +1 more source

Intracellular calcium signaling [PDF]

Journal of Cell Science, 2002
In excitable cells, the major pathway for Ca2+ influx is via highly Ca2+-selective voltage-gated Ca2+ channels (VGCC). The original alphabetical nomenclature was replaced recently with standard numerical nomenclature: Cav1.1-1.4, Cav2.1-2.3, Cav3.1-3.3.
Martha C, Nowycky, Andrew P, Thomas
openaire   +2 more sources

Lipid Signaling During Gamete Maturation

Frontiers in Cell and Developmental Biology, 2022
Cell lipids are differentially distributed in distinct organelles and within the leaflets of the bilayer. They can further form laterally defined sub-domains within membranes with important signaling functions.
Sherif Mostafa, Nancy Nader, Nancy Nader, Khaled Machaca, Khaled Machaca   +4 more
doaj   +1 more source

Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium [PDF]

, 2013
Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such
A Gnoni, A Pace, A Sharma, AJ Hietaranta, AK Saluja, AK Saluja, AS Gukovskaya, B Han, B Han, B Hofbauer, B Kruger, C Schafer, Catherine J. Baty, CH Kubisch, Chandra Durgampudi, Chathur Acharya, DN Criddle, Donna B. Stolz, EC Thrower, EM Parker, F Gorelick, F Mooren, F Nozu, G Lynch, H Weber, HK Baumgartner, I Gukovsky, I Gukovsky, I Samuel, JA Tapia, JA Williams, Jenny Karlsson, JV Gerasimenko, KA Muili, Krutika Patel, L Fischer, L Orlichenko, Lidiya Orlichenko, LJ Christopher, LJ Lombardo, LS Orlichenko, M Sendler, MS O'Konski, OA Mareninova, OH Petersen, Pawan Noel, PC Redondo, Rachel Cline, Ram Narayan Trivedi, RD Duan, RR Torgerson, RR Torgerson, S Kawabata, S Navina, Sarah Navina, SD Waterford, SG Weller, SJ Pandol, Sohail Z. Husain, Stuart E. Dryer, SZ Husain, SZ Husain, T Eley, T Grady, T Grady, V Sancho, Vijay P. Singh, Vivek Mishra, VP Singh, VP Singh, VP Singh, VP Singh, Y Tsunoda   +72 more
core   +6 more sources

Calcium signaling [PDF]

Cell, 1995
Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles.
openaire   +3 more sources

Novel Mutations in a Lethal Case of Lymphomatous Adult T Cell Lymphoma with Cryptic Myocardial Involvement

Current Oncology, 2021
The autopsy of a 65-year-old diabetic African American male revealed significant left myocardial involvement by adult T-cell leukemia/lymphoma (ATLL) despite normal pre-mortem fluorodeoxyglucose (FDG) uptake by positron emission tomography/computed ...
Taraneh Hashemi Zonouz, Rami Abdulbaki, Bidhan C. Bandyopadhyay, Victor E. Nava   +3 more
doaj   +1 more source