Results 71 to 80 of about 6,142,205 (404)
Imaging mitochondrial calcium dynamics in the central nervous system [PDF]
Journal of Neuroscience Methods, 2022, 373, pp.109560Mitochondrial calcium handling is a particularly active research area in the neuroscience field, as it plays key roles in the regulation of several functions of the central nervous system, such as synaptic transmission and plasticity, astrocyte calcium signaling, neuronal activity{\ldots} In the last few decades, a panel of techniques have been ...
arxiv +1 more source
Characterization of biophysical determinants of spatio-temporal calcium dynamics in astrocytes [PDF]
arXiv, 2021 Most of the functions performed by astrocytes in brain information processing are related to calcium waves. Experimental studies involving calcium waves present discrepant results, leading to gaps in the full understanding of the functions of these cells.
arxiv
Calcium Signaling and Tissue Calcification.
Cold Spring Harbor Perspectives in Biology, 2019 Calcification is a regulated physiological process occurring in bones and teeth. However, calcification is commonly found in soft tissues in association with aging and in a variety of diseases. Over the last two decades, it has emerged that calcification
D. Proudfoot
semanticscholar +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
Nonequilibrium calcium dynamics optimizes the energetic efficiency of mitochondrial metabolism [PDF]
arXiv, 2023 Living organisms continuously harness energy to perform complex functions for their adaptation and survival while part of that energy is dissipated in the form of heat or chemical waste. Determining the energetic cost and the efficiency of specific cellular processes remains a largely open problem.
arxiv
Calcium Signaling Pathways: Key Pathways in the Regulation of Obesity
International Journal of Molecular Sciences, 2019 Nowadays, high epidemic obesity-triggered hypertension and diabetes seriously damage social public health. There is now a general consensus that the body’s fat content exceeding a certain threshold can lead to obesity.
Ziguo Song +4 more
semanticscholar +1 more source
Calcium signaling in lymphocytes [PDF]
Current Opinion in Immunology, 2008 In cells of the immune system, calcium signals are essential for diverse cellular functions including differentiation, effector function, and gene transcription. After the engagement of immunoreceptors such as T-cell and B-cell antigen receptors and the Fc receptors on mast cells and NK cells, the intracellular concentration of calcium ions is ...
Anjana Rao, Masatsugu Oh-hora
openaire +3 more sources
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Physiological Function and Characterization of TRPCs in Neurons
Cells, 2014 Ca2+ entry is essential for regulating vital physiological functions in all neuronal cells. Although neurons are engaged in multiple modes of Ca2+ entry that regulates variety of neuronal functions, we will only discuss a subset of specialized Ca2 ...
Yuyang Sun +3 more
doaj +1 more source
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source