Results 71 to 80 of about 28,592 (236)
PLoS ONE, 2023 βA3/A1-crystallin is a lens structural protein that plays an important role in maintaining lens transparency via interactions with other crystallins. While the function of βA3/A1-crystallin in the retina is well studied, its functions in the lens, other ...
Roy Joseph +3 more
doaj +1 more source
Calpain 3, the “gatekeeper” of proper sarcomere assembly, turnover and maintenance [PDF]
Neuromuscular Disorders, 2008 Calpain 3 is a member of the calpain family of calcium-dependent intracellular proteases. Thirteen years ago it was discovered that mutations in calpain 3 (CAPN3) result in an autosomal recessive and progressive form of limb girdle muscular dystrophy called limb girdle muscular dystrophy type 2A.
Jacques S, Beckmann, Melissa, Spencer
openaire +2 more sources
Auditory Stimulation of Slow‐Wave Sleep Promotes Recovery after Brain Injury in an Animal Model
Annals of Neurology, EarlyView.Objective Traumatic brain injury (TBI) significantly reduces the quality of life for millions of survivors worldwide, causing persistent brain tissue damage and cognitive impairments, with no established therapeutic interventions currently available.
Carlos G. Moreira +9 more
wiley +1 more source
Mutationen im \(\it Calpain\) 3-Gen
, 2005 Die Untersuchungen der Dissertation befassen sich mit einer autosomal-rezessiv vererbten Gliedergürtel-Muskeldystrophie, der Calpainopathie (LGMD2A), die durch Mutationen im \(\it CAPN3\)-Gen verursacht wird. Das Ziel der durchgeführten Studie bestand darin, in einem Patientenkollektiv von 34 Patienten Mutationen im \(\it CAPN3\)-Gen darzustellen.
openaire +3 more sources
Animal Production: Indonesian Journal of Animal Production, 2012 . The purpose of research was to investigate whether there was influence of the addition of concentrates in basal feed on meat tenderness and calpastatin and calpain activities of three muscles of Kejobong does.
M Socheh +3 more
doaj
Journal of Inflammation, 2009 Background The peptidyl-proline isomerase, Protein Never in Mitosis Gene A Interacting-1 (PIN1), regulates turnover of inducible nitric oxide synthase (iNOS) in murine aortic endothelial cells (MAEC) stimulated with E. coli endotoxin (LPS) and interferon-
Likhotvorik Rostislav I +6 more
doaj +1 more source
Different roles for contracture and calpain in calcium paradox-induced heart injury. [PDF]
PLoS ONE, 2012 The Ca(2+) paradox represents a good model to study Ca(2+) overload injury in ischemic heart diseases. We and others have demonstrated that contracture and calpain are involved in the Ca(2+) paradox-induced injury.
Jian-Ying Zhang +8 more
doaj +1 more source
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Calpain-mediated degradation of GFAP at 2 h following blast injury.
, 2017 Proteins were isolated from sham control (Sham), low-blast (L-Blast), and high-blast (H-Blast) OHCs at 2 h post-injury and analyzed via western blot for expression of GFAP (A, B) or calpain (C).
Brandy V. Aperi (3815545) +5 more
core +1 more source
Characterization of levels of calpain-3 activity in βA3cKO wild-type lenses.
, 2023 Calpain activity was determined using N-succinyl-leu-tyr-7-amido-4 methyl coumarin as a substrate. (A) Basal calpain activity in absence of calcium chloride in homogenates of βA3cKO- and wild-type lenses.
Laura Lambert (10683666) +3 more
core +1 more source