Results 111 to 120 of about 12,091 (231)

Sequential mutational evaluation of CALR ‐mutated myeloproliferative neoplasms with thrombocytosis reveals an association between CALR allele burden evolution and disease progression

, 2019
International audienceIn myeloproliferative neoplasms (MPN), JAK2V617F allele burden measurement has an impact on prognosis that helps in patient monitoring. Less is known about its usefulness in CALR‐mutated cases.
Lippert, Eric, Jean Christophe Ianotto, Ianotto, Jean Christophe, Jean‐Marie Chrétien, QUINTIN-ROUÉ, Isabelle, Maxime Renard, Orvain, Corentin, Sophie Sadot‐Lebouvier, Truchan‐Graczyk, Matgorzata, CHRÉTIEN, Jean-Marie, Chrétien, Jean‐Marie, TRUCHAN-GRACZYK, Matgorzata, Boyer, Françoise, HUNAULT-BERGER, Mathilde, Luque Paz, Damien, Damien Luque Paz, Cottin, Laurane, Olivier Mansier, Françoise Boyer, Mathilde Hunault‐Berger, Sadot‐Lebouvier, Sophie, Valérie Ugo, Allangba, Olivier, Eric Lippert, Mansier, Olivier, Corentin Orvain, Jouanneau‐Courville, Rebecca, Yves Delneste, Hunault‐Berger, Mathilde, Matgorzata Truchan‐Graczyk, Anne Murati, Rébecca Jouanneau‐Courville, Riou, Jeremie, Antoine Martin, Olivier Allangba, Jérémie Riou, Delneste, Yves, Ugo, Valérie, Rousselet, Marie-Christine, Martin, Antoine, JOUANNEAU-COURVILLE, Rébecca, Burroni, Barbara, Murati, Anne, Quintin‐Roué, Isabelle, Laurane Cottin, Odile Blanchet, Blanchet, Odile, SADOT-LEBOUVIER, Sophie, Isabelle Quintin‐Roué, Barbara Burroni, Renard, Maxime, Marie-Christine Rousselet   +51 more
core   +1 more source

Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Eight trained males completed 4 days of normal‐carbohydrate or low‐carbohydrate (81% reduction in carbohydrate) diets while maintaining energy balance and undertaking daily exercise. Low carbohydrate decreased total body water and fat‐free mass, increased circulating free fatty acids, glycerol and β‐hydroxybutyrate, alongside increased fat oxidation at
Erick Mosquera‐Lopez, Harry L. Taylor, Yusuke Nishimura, Carl Langan‐Evans, Sam O. Shepherd, Juliette A. Strauss, James P. Morton, Jatin G. Burniston, Jose L. Areta   +8 more
wiley   +1 more source

The characteristics of CALR mutations in myeloproliferative neoplasms: a clinical experience from a tertiary care center in Qatar and a literature review

Hematology
Background Myeloproliferative neoplasms (MPNs) are hematological disorders characterized by abnormal production of myeloid cells due to genetic mutations.
Mostafa Najim, Mohammad Abu-Tineh, Awni Alshurafa, Mohamed Izham Mohamed Ibrahim, Soubiya Ansari, Hazem Faraj, Saif Alateeg, Susanna Jane Akiki, Mohamed A. Yassin   +8 more
doaj   +1 more source

Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm

, 2016
Yarden S Fraiman,1,2 Nathan Cuka,3 Denise Batista,3 Milena Vuica-Ross,3 Alison R Moliterno4 1Department of Pediatrics, Harvard Medical School, 2Department of Pediatrics, Boston University School of Medicine, Boston, MA, 3Department of Pathology ...
Cuka N, Batista D, Moliterno AR, Fraiman YS, Vuica-Ross M   +4 more
core  

Fenofibrate Protects Against Antipsychotic‐Induced Hyperglycemia Through Weight Loss and FGF21 Dependent Mechanisms

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
The proposed mechanism through which fenofibrate protects against olanzapine‐induced hyperglycemia in mice. ABSTRACT Antipsychotic (AP) medications, such as olanzapine, cause acute weight gain independent of hyperglycemia through a glucagon‐dependent mechanism.
Michael Akcan, Stewart Jeromson, Bradley J. Baranowski, Annalaura Bellucci, Serena Trang, Katelyn Eisner, Ailish Babicki‐Moore, Hadil Alfares, Meagan Arbeau, Kyle Medak, Margaret Hahn, David C. Wright   +11 more
wiley   +1 more source

CALRETICULIN IN MYELOPROLIFERATIVE NEOPLASMS: THE OTHER SIDE OF THE ALICE MIRROR [PDF]

European Medical Journal Hematology, 2014
Calreticulin (CALR), a Ca2+ binding protein mostly localised in the endoplasmic reticulum, regulates Ca2+ homeostasis, chaperones, and other proteins to the nucleus and other cellular compartments.
Lilian Varricchio, Anna Rita Migliaccio
doaj  

Progenitor genotyping reveals a complex clonal architecture in a subset of CALR-mutated myeloproliferative neoplasms

, 2017
The identification of acquired CALR mutations in patients with essential thrombocythaemia (ET) or myelofibrosis (MF) has meant that disease-initiating mutations can now be detected in about 90% of all patients with a myeloproliferative neoplasm (MPN ...
Scott, Linda M., Martin, Sarah, Wright, Casey M.   +2 more
core   +1 more source

The risk of thrombosis in essential thrombocythemia is associated with the type of CALR mutation: A multicentre collaborative study

, 2020
Objectives: In patients with essential thrombocythemia (ET), after the JAK2V617F driver mutation, mutations in CALR are common (classified as type 1, 52‐bp deletion or type 2, 5‐bp insertion).
Ferrer‐Marín, Francisca, Quinteiro García, Celsa, Łukasz, Szukalski, Fox, María Laura, Martín Martín, Alejandro, González Martín, Jesús María, Gasior Kabat, Mercedes, Gómez Casares, María Teresa, Noya Pereira, María Soledad, Raya, José María, Gołos, Aleksandra, Pérez Encinas, Manuel M., Magro Mazo, Elena, Sobas, Marta, Stuckey, Ruth, Álvarez Larrán, Alberto, Bellosillo Paricio, Beatriz, Lewandowski, Krzysztof, Czyż, Anna, Andrade‐Campos, Marcio M., Hernández Boluda, Juan Carlos, Abuin Blanco, Aitor   +21 more
core   +1 more source

CALR mutations in myeloproliferative neoplasms: An unfolding story

EXCLI journal, 2020
EXCLI Journal; 19:Doc1399; ISSN 1611 ...
openaire   +2 more sources

Results of CALR mutations among 83 ET patients.

, 2015
Results of CALR mutations among 83 ET patients.
Serge Carillo (818264), Ji-Hye Park (284710), Dominique Bouchot (818255), Mathilde Bas (818257), François Girodon (818265), Laurent Martin (818262), Aurélie Truffot (818253), Margaux Sevin (818251), Martine Courtois (818256), Selim Ramla (818252), Sonia Benali (818258), François Bailly (818259), Julien Guy (818261), Tiffany Verrier (818254), Bernardine Favre (818260), Marc Maynadié (818263)   +15 more
core   +1 more source