Results 31 to 40 of about 8,051 (219)
Earth, Water, Fleece and Fabric: an ethnography and archaeology of Andean camelid herding
, 2002 Earth, Water, Fleece and Fabric is a collection of images that accompanies the book 'Earth, Water, Fleece and Fabric: An Ethnography and Archaeology of Andean Camelid Herding'.
Penny Dransart
core +1 more source
Camelid immunoglobulins and nanobody technology [PDF]
Veterinary Immunology and Immunopathology, 2009 It is well established that all camelids have unique antibodies circulating in their blood. Unlike antibodies from other species, these special antibodies are devoid of light chains and are composed of a heavy-chain homodimer. These so-called heavy-chain antibodies (HCAbs) are expressed after a V-D-J rearrangement and require dedicated constant gamma ...
Muyldermans, S +16 more
openaire +5 more sources
Developing drug-like single-domain antibodies (VHH) from in vitro libraries
mAbsHere, we describe a new VHH library for therapeutic discovery which optimizes humanness, stability, affinity, diversity, developability, and facile purification using protein A in the absence of an Fc domain.
M. Frank Erasmus +14 more
doaj +1 more source
Hypoosmotic swelling test in alpaca (Vicugna pacos) spermatozoa recovered the vas deferens [PDF]
SPERMOVA, 2015 The study objective was to evaluate the endosmotic reaction in 5 hypoosmotic solutions 100, 125, 150, 175 and 200 mOsm/l (HOS test) incubated 5 and 15 minutes using alpaca sperm recovered the vas deferens.
Quispe HA +4 more
doaj +1 more source
Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
Emerging Infectious Diseases, 2023 Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended shedding of MERS-CoV clade B viruses in llamas, which
Jordi Rodon +13 more
doaj +1 more source
npj VirusesThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects a variety of animal species. Susceptibility to SARS-CoV-2 is primarily determined by the utilization of the viral receptor, ACE2. SARS-CoV-2 can utilize a broad range of animal ACE2
Tim I. Breugem +7 more
doaj +1 more source
Frontiers in Genetics, 2019 Structural chromosome abnormalities, such as translocations and inversions occasionally occur in all livestock species and are typically associated with reproductive and developmental disorders.
Malorie P. Baily +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
A Generative Neuro‐Symbolic AI for Protein Sequence Design
Advanced Science, EarlyView.We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
mAbs, 2020 Here, we report the characterization of a VHH-derived IgG-like bi- and trispecific antibody platform that essentially relies on the replacement of the VH and VL regions of a conventional antibody by two independently functioning VHH domains. Consequently,
Lukas Pekar +6 more
doaj +1 more source