Results 31 to 40 of about 8,334 (239)
Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
Emerging Infectious Diseases, 2023 Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended shedding of MERS-CoV clade B viruses in llamas, which
Jordi Rodon +13 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
"Palaeoproteomics of Andean Camelid fibers" project DMP
"Palaeoproteomics of Andean Camelid fibers" project ...
Zirah, Séverine +3 more
core +3 more sources
Enhancing Stability of Camelid and Shark Single Domain Antibodies: An Overview
Frontiers in Immunology, 2017 Single domain antibodies (sdAbs) are gaining a reputation as superior recognition elements as they combine the advantages of the specificity and affinity found in conventional antibodies with high stability and solubility.
Ellen R. Goldman +3 more
doaj +1 more source
mAbs, 2020 Here, we report the characterization of a VHH-derived IgG-like bi- and trispecific antibody platform that essentially relies on the replacement of the VH and VL regions of a conventional antibody by two independently functioning VHH domains. Consequently,
Lukas Pekar +6 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Novel therapy based on camelid nanobodies
, 2013 Nanobodies (Nbs) are small antibody fragments derived from camelid heavy chain antibodies through recombinant gene technology. Their exceptional physicochemical properties, possibility of humanization and unique antigen recognition properties make them ...
Del Castillo, Teresa +10 more
core +1 more source
Relationship between isotopic and elemental composition of camelid fiber textiles.
, 2020 Carbon and nitrogen isotopic compositions of textiles analyzed in this study, as well as other camelid fiber samples from previously published papers [26, 31, 32]. Samples are colored according to their atomic C:N ratio.
Paul Szpak (102595) +1 more
core +1 more source
Basal Levels and hCG Responses of Serum Testosterone and Estrogen in Male Alpacas
Frontiers in Veterinary Science, 2020 Steroid response to human Chorionic Gonadotropin (hCG) administration has been used in various species to study testicular function and for diagnostic purposes.
Aymen El Zawam +2 more
doaj +1 more source