Results 51 to 60 of about 12,569 (240)

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Nanobody based dual specific CARs [PDF]

open access: yes, 2018
Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas.
Abken, Hinrich   +8 more
core   +2 more sources

Living Microbial Drugs

open access: yesChemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik   +3 more
wiley   +1 more source

Single-domain antibody fragments derived from heavy-chain antibodies: a review

open access: yesVeterinární Medicína, 2012
Single-domain antibody (sdAb) fragments derived from heavy-chain antibodies of camelids and cartilaginous fish represent a new generation of therapeutic agents and immunoreagents.
L. Eyer, K. Hruska
doaj   +1 more source

Colostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1

open access: yesJournal of Immunotoxicology, 2020
Exposure to environmental toxicants that affect the immune system and overall health of many mammals is mostly unavoidable. One of the more common substances is the mycotoxins, especially carcinogenic aflatoxin (AF)B1 which also causes immune suppression/
Sajad Najafi   +4 more
doaj   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Pairing Alpaca and Llama-Derived Single Domain Antibodies to Enhance Immunoassays for Ricin

open access: yesAntibodies, 2017
Previously, our group isolated and evaluated anti-ricin single domain antibodies (sdAbs) derived from llamas, engineered them to further increase their thermal stability, and utilized them for the development of sensitive immunoassays. In work focused on
Kendrick B. Turner   +6 more
doaj   +1 more source

Socio-economic indicators of the camel production sector in southeast Tunisia: main households survey results [PDF]

open access: yes, 2015
This Socio-economic study has been conducted by a team of PROCAMED Project. This project falls within the framework of the promotion of the innovating camel systems and of the local camel value chains for a sustainable management of the Saharan ...
Faye, Bernard   +3 more
core  

Structural insights and biomedical potential of IgNAR scaffolds from sharks [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Barelle, Caroline   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy