Results 281 to 290 of about 11,333,085 (312)
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PTEN in cancer associated fibroblasts
2022Decades of research have concluded that disruptions to Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) have profound effects on cancer progression. However, as our understanding of the tumor stroma has evolved, we can appreciate that disruptions to tumor suppressors such as PTEN should not be studied solely in an epithelial context ...
Julia E, Lefler +2 more
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2023
This webinar will focus on Cancer-associated fibroblasts. Our panelists will discuss developments in this exciting research field and their global perspectives. Prof Neta Erez will be speaking about how stromal plasticity shapes the metastatic microenvironment and Dr Ruth Scherz-Shouval will be speaking about cancer-CAF coevolution. Dr.
Neta Erez +3 more
openaire +1 more source
This webinar will focus on Cancer-associated fibroblasts. Our panelists will discuss developments in this exciting research field and their global perspectives. Prof Neta Erez will be speaking about how stromal plasticity shapes the metastatic microenvironment and Dr Ruth Scherz-Shouval will be speaking about cancer-CAF coevolution. Dr.
Neta Erez +3 more
openaire +1 more source
Cancer-associated fibroblasts in colorectal cancer
Clinical and Translational Oncology, 2021Colorectal cancer (CRC) is one of the leading causes of mortality among cancers. Many aspects of this cancer are under investigation to find established markers of diagnosis, prognosis, and also potential drug targets. In this review article, we are going to discuss the possible solution to all these aims by investigating the literature about cancer ...
S. Kamali Zonouzi +3 more
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Cancer-Associated Fibroblasts in Pancreatic Adenocarcinoma
Future Oncology, 2015Pancreatic ductal adenocarcinoma (PDAC) is one of the most highly malignant tumors with a very poor prognosis. In addition to the cancer cells, the stroma of tumor can expand by 50% and influence cancer cell growth. Cancer-associated fibroblasts (CAFs) are important components of tumor stroma.
Boju, Pan +4 more
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The plasticity of cancer-associated fibroblasts
Trends in CancerThe plasticity of cancer-associated fibroblasts (CAFs) refers to their ability to adopt a spectrum of distinct phenotypes or states in response to dynamic changes within the tumor microenvironment (TME). Recent advances in single-cell technologies have enabled detailed characterization of the heterogeneity and spatial complexity of CAF subpopulations ...
Zihan Xia, Olivier De Wever
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Isolation of Normal and Cancer-Associated Fibroblasts
2021Cancer-associated fibroblasts (CAFs) play important roles in regulating tumor progression, metastasis, and response to therapies. Accurately modeling the interplay between cancer cells and the tumor microenvironment (TME) requires the use of primary cells from patient samples.
Katarzyna, Zawieracz, Mark A, Eckert
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Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma
Current Opinion in Gastroenterology, 2011The aim of this brief review is to provide an up-to-date view of the role played by α-smooth muscle actin-positive cancer-associated fibroblastic cells in promoting intrahepatic cholangiocarcinoma progression.An increase in α-smooth muscle actin-positive cancer-associated fibroblastic cells in the stroma of intrahepatic cholangiocarcinoma has recently ...
Alphonse E, Sirica +2 more
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Cancer-associated fibroblasts in papillary thyroid carcinoma
Clinical and Experimental Medicine, 2023Papillary thyroid carcinoma (PTC) has a relatively good prognosis, yet there are some invasive PTC cases with worse clinicopathological features and poor outcome. Cancer-associated fibroblasts (CAFs) play an important role in cancer invasion and metastasis.
Li, Zhu +15 more
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