Results 1 to 10 of about 2,928,478 (311)
Design considerations of an IL13Rα2 antibody–drug conjugate for diffuse intrinsic pontine glioma
Acta Neuropathologica Communications, 2021 Diffuse intrinsic pontine glioma (DIPG), a rare pediatric brain tumor, afflicts approximately 350 new patients each year in the United States. DIPG is noted for its lethality, as fewer than 1% of patients survive to five years.
Xiaolei Lian +6 more
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Acta Neuropathologica Communications, 2021 An amendment to this paper has been published and can be accessed via the original article.
Xiaolei Lian +6 more
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Molecular Cancer, 2023 Background Chimeric Antigen Receptor (CAR) T cells are now standard of care (SOC) for some patients with B cell and plasma cell malignancies and could disrupt the therapeutic landscape of solid tumors.
Hyatt Balke-Want +16 more
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Preclinical therapeutics ex ovo quail eggs as a biomimetic automation-ready xenograft platform
Scientific Reports, 2021 Preclinical cancer research ranges from in vitro studies that are inexpensive and not necessarily reflective of the tumor microenvironment to mouse studies that are better models but prohibitively expensive at scale. Chorioallantoic membrane (CAM) assays
Samuel V. Rasmussen +6 more
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Zhongliu Fangzhi Yanjiu, 2021 Objective To evaluate the technical feasibility and safety of a single-incision technique via axillary vein (AV) for placement of totally implantable venous access port (TIVAP) guided by ultrasound combined with DSA in clinical application.
LIU Weifu +4 more
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Radiation Oncology, 2022 Background Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases.
Masanori Hirata +15 more
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Deep learning method for prediction of patient-specific dose distribution in breast cancer
Radiation Oncology, 2021 Background Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-sided
Sang Hee Ahn +10 more
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Towards Personalized Prostate Cancer Therapy Using Delta-Reachability Analysis [PDF]
, 2015 Recent clinical studies suggest that the efficacy of hormone therapy for prostate cancer depends on the characteristics of individual patients. In this paper, we develop a computational framework for identifying patient-specific androgen ablation therapy
Biere A. +7 more
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Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]
, 2012 The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J. +2 more
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Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database [PDF]
, 2017 For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were ...
Bradley, Jeffrey D +10 more
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