Results 51 to 60 of about 1,412,519 (351)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Poultry Science: Small peptides are nutrients and bioactive molecules that have dual regulatory effects on nutrition and physiology. They are of great significance for maintaining the intestinal health and production performance of broilers.
Jing Liang +6 more
doaj +1 more source
Genetics and Molecular Biology, 2009 Several quantitative trait loci (QTL) for important reproductive traits (ovulation rate) have been identified on the porcine chromosome 15 (SSC15). To assist in the selection of positional candidate swine genes for these QTL on SSC15, twenty-one genes ...
Hongli Du +4 more
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Cross-Disorder Analysis of De Novo Variants Increases the Power of Prioritising Candidate Genes
Life, 2021 De novo variants (DNVs) are critical to the treatment of neurodevelopmental disorders (NDDs). However, effectively identifying candidate genes in small cohorts is challenging in most NDDs because of high genetic heterogeneity.
Kuokuo Li +8 more
doaj +1 more source
Genome-wide superior alleles, haplotypes and candidate genes associated with tolerance on sodic-dispersive soils in wheat (Triticum aestivum L.) [PDF]
, 2022 Darshan Sharma +5 more
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hagis, an R Package Resource for Pathotype Analysis of Phytophthora sojae Populations Causing Stem and Root Rot of Soybean [PDF]
, 2019 Phytophthora sojae is a significant pathogen of soybean worldwide. Pathotype surveys for Phytophthora sojae are conducted to monitor resistance gene efficacy and determine if new resistance genes are needed.
Chilvers, Martin +3 more
core +2 more sources
Experimental and Clinical Gastroenterology, 2021 Hereditary predisposition is one of the aetiopathogenetic factors in the development of gastric ulcer and duodenal ulcer. The analysis of literature materials allows us to identify a number of candidate genes that play a role in the formation of peptic ulcer: PSCA, ABO, IL1β, IL1RN, TNFα, HSP70-1, GSR, TLR4, TLR2, TLR9, MMP-1, MMP-3, MMP- 9, TIMP-3 ...
O. V. Rashina, M. I. Churnosov
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Differential allelic expression of IL13 and CSF2 genes associated with asthma
Genetics and Molecular Biology, 2012 An important area of genetic research is the identification of functional mechanisms in polymorphisms associated with diseases. A highly relevant functional mechanism is the influence of polymorphisms on gene expression levels (differential allelic ...
Jana Burkhardt +4 more
doaj
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source