Results 81 to 90 of about 23,909 (233)

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

open access: yesAddiction, EarlyView.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez   +5 more
wiley   +1 more source

Cannabinoids in neurology – Brazilian Academy of Neurology

open access: yesArquivos de Neuro-Psiquiatria, 2015
The use of cannabidiol in some neurological conditions was allowed by Conselho Regional de Medicina de São Paulo and by Agência Nacional de Vigilância Sanitária (ANVISA).
Sonia M. D. Brucki   +12 more
doaj   +1 more source

A Longitudinal Assessment of Endometriosis Patients Prescribed Cannabis‐Based Medicinal Products: A Case Series From the UK Medical Cannabis Registry

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter   +16 more
wiley   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
Cannabidiol and cannabigerol suppress maximal electroshock seizures. Cannabidiol and cannabigerol show similar dose–response properties. Both cannabinoids show no toxicity at effective doses. ABSTRACT Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population.
Zhou HZ   +3 more
europepmc   +2 more sources

A Scoping Systematic Review of Cannabis Use in Endometriosis

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Endometriosis, affecting 6%–10% of reproductive‐age women, causes chronic pelvic pain, dysmenorrhea, and infertility. Current treatments have limitations and consequently there is rising interest in effects of cannabis on pain and inflammation associated with endometriosis.
Kindha McLaren   +2 more
wiley   +1 more source

∆9-THC intoxication by cannabidiol-enriched cannabis extract in two children with refractory epilepsy: full remission after switching to purified cannabidiol

open access: yesFrontiers in Pharmacology, 2016
Animal studies and preliminary clinical trials have shown that cannabidiol-enriched extracts may have beneficial effects for children with treatment-resistant epilepsy.
José Alexandre Crippa   +4 more
doaj   +1 more source

The Recruitment and Retention of Individuals With Intellectual Disability in Randomized Controlled Trials: A Scoping Review

open access: yesBritish Journal of Learning Disabilities, EarlyView.
ABSTRACT Background People with intellectual disabilities face significant health disparities and often encounter barriers in accessing healthcare services. Although research supports the need for reasonable adjustments to improve healthcare access for this population, implementation in acute healthcare settings remains limited.
Owen Doody   +5 more
wiley   +1 more source

Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome [PDF]

open access: gold, 2020
Évila Lopes Salles   +9 more
openalex   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy