Results 1 to 10 of about 60,949 (210)
Cannabinoid‐Induced Hyperphagia is Mediated by Increased Meal Frequency and the Orexin‐1 Receptor in Male Rats [PDF]
Pharmacology Research & PerspectivesExogenous cannabinoids have long been known to promote eating. However, the underlying mechanisms have not been completely elucidated, which is critical to understanding their utility.
Magen N. Lord +5 more
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Cancers, 2021 Cannabinoids, active components of the plant Cannabis sativa, had been used for centuries in ancient medicine as therapeutic remedies for a variety of conditions, before becoming stigmatized due to their psychoactive effects [...]
Marco Falasca, Mauro Maccarrone
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Journal of Cannabis Research, 2022 Aim We undertook this systematic review to determine the efficacy and safety of cannabis-based medicine as a treatment for behavioral, psychological, and motor symptoms associated with neurocognitive disorders.
Anees Bahji +6 more
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BMC Primary Care, 2022 Background Medicinal cannabis (MC) products have been available on prescription in Australia for around six years. General practitioners (GPs) are at the forefront of MC prescribing and recent years have seen substantial increases in prescription numbers.
Zeeta Bawa +3 more
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Medical Cannabis and Cannabinoids, 2018 Cannabinoid hyperemesis syndrome (CHS) is a paradoxical condition in which a long-term cannabis user suffers an episode of intractable vomiting that may last days separated by longer asymptomatic periods of weeks or months. Cannabinoids are often utilized for their antiemetic properties, so CHS can be a puzzling condition, and the diagnosis of CHS may ...
Joseph V. Pergolizzi Jr. +2 more
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Harm Reduction Journal, 2022 Background Australia has had a framework for legal medicinal cannabis since 2016, yet prior online surveys in 2016 and 2018 indicated that most consumers continued to use illicit medical cannabis products.
Nicholas Lintzeris +5 more
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OncoImmunology, 2023 During solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive milieu. Key players in the immunosuppressive environment are regulatory myeloid cells, including myeloid-derived suppressor cells (MDSCs) and tumor ...
Iris Wyrobnik +9 more
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Heteroadamantyl Cannabinoids [PDF]
Journal of Medicinal Chemistry, 2010 The aliphatic side chain plays a pivotal role in determining the cannabinergic potency of tricyclic classical cannabinoids. We have synthesized a series of analogues in which the C3 position is substituted either directly or through a one-carbon atom linker with an adamantylamine or with an oxa- or an oxazaadamantane. The oxaadamantane pharmacophore in
Darryl D, Dixon +8 more
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The safety and efficacy of low oral doses of cannabidiol: An evaluation of the evidence
Clinical and Translational Science, 2023 Global interest in the non‐intoxicating cannabis constituent, cannabidiol (CBD), is increasing with claims of therapeutic effects across a diversity of health conditions.
Jonathon C. Arnold +3 more
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BMJ Case Reports, 2010 A 21-year-old woman presented with a 4-week history of sudden onset vomiting, nausea and anorexia. Questioning revealed that she had a 7-year history of heavy cannabis use (smoking). She did not describe abdominal pain, change in bowel habit, antibiotic use, foreign travel or contact with gastroenteritis.
Kim, Wild, Hugh, Wilson
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