Results 171 to 180 of about 74,377 (332)

Deceptive beauty of non‐natural structures

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich, Eugenia V. Gurevich   +1 more
wiley   +1 more source

Synthesis of quinolinyl and isoquinolinyl phenyl ketones as novel agonists for the cannabinoid CB2 receptor

, 2009
Bastien Reux, Tapio Nevalainen, Katri H. Raitio, Ari M. P. Koskinen   +3 more
openalex   +2 more sources

Fasting Induces CART Down-Regulation in the Zebrafish Nervous System in a Cannabinoid Receptor 1-Dependent Manner [PDF]

, 2012
Shin‐ichi Nishio, Yann Gibert, Liubov Berekelya, Laure Bernard, Frédéric Brunet, Etienne Guillot, Jean-Christophe Le Bail, Juan Antonio Sánchez‐Alcañiz, Anne Marie Galzin, Gérard Triqueneaux, Vincent Laudet   +10 more
openalex   +1 more source

Changing trends in drug overdose mortality in Spain, 2001–2022

Addiction, Volume 121, Issue 2, Page 261-272, February 2026.
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné, Marta Donat, Juan Miguel Guerras, Gregorio Barrio, María José Belza, Julieta Politi, Enrique Regidor   +6 more
wiley   +1 more source

Cannabinoid-1 receptor antagonists reduce caloric intake by decreasing palatable diet selection in a novel dessert protocol in female rats

, 2008
Clare M. Mathes, Marco Ferrara, Neil E. Rowland   +2 more
openalex   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
Cannabidiol and cannabigerol suppress maximal electroshock seizures. Cannabidiol and cannabigerol show similar dose–response properties. Both cannabinoids show no toxicity at effective doses. ABSTRACT Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population.
Han Zhong Zhou, Brian Wayne Scott, Yagoda Izabela Oleksak, Willets McIntyre Burnham   +3 more
wiley   +1 more source

Targeting mechanosensitive cannabinoid receptor 1 with isoflavone prodrugs attenuates atherosclerotic endothelial dysfunction. [PDF]

J Biomed Sci
Chung DJ, Chen SP, Liu WH, Liu CY, Su NW, Hsu C, Tsai HY, Yang KC, Wu CK, Lin SW, Shie JJ, Zhao MT, Wei TT.   +12 more
europepmc   +1 more source

Agricultural System Resilience of Industrial Hemp: An Exploratory Value Web Analysis in the Swabian Alb

GCB Bioenergy, Volume 18, Issue 2, February 2026.
This study assessed the industrial hemp value web resilience in the Swabian Alb, Southern Germany, where regional implementation remains limited despite hemp's bioeconomy potential. Using an indicator framework and stakeholder interviews, the research found the small, fluctuating cultivation area (e.g., 25 ha in 2024) focuses on hemp seed valorisation;
Lena‐Sophie Loew, Moritz von Cossel
wiley   +1 more source

Insights into cannabinoid receptor 2 (CB2) anterograde trafficking and pharmacological chaperoning. [PDF]

Cell Mol Life Sci
Oyagawa CRM, Woodhouse B, Wood KC, Glass M, Grimsey NL.   +4 more
europepmc   +1 more source

Synthetic Cannabinoid Use and Sports‐Related Concussion Risk Among US Adolescents: Implications for School Health Screening and Prevention

Journal of School Health, Volume 96, Issue 2, February 2026.
ABSTRACT Background Synthetic cannabinoids (SCs), such as Spice and K2, appeal to adolescents because they are inexpensive and often evade standard drug tests. We assessed associations between SC use and sports‐related traumatic brain injuries (TBIs) among US adolescents.
Saurabh Kalra, Nandakumar Nagaraja, Deepak Kalra   +2 more
wiley   +1 more source