Results 171 to 180 of about 2,668,334 (282)

Impact of a substance use screening program on racial disparities in urine toxicology testing

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Objective To evaluate whether implementing a standardized substance use screening program reduced racial disparities in urine toxicology (Utox) testing among delivery admissions. Methods We conducted a retrospective cohort study of delivery admissions at a single academic center from June 2019 to June 2025. To address known disparities in Utox
Mariam Naqvi, Amin Tavakoli, Camelita S. Thrift, Allison Henry, Jennifer Astasio, Farnaaz Kia, Naomi Greene, Sarah J. Kilpatrick   +7 more
wiley   +1 more source

Opposing Synovial Cannabinoid Receptor Type 2 and Transient Receptor Potential Vanilloid 1 Expression in Painful Osteoarthritis. [PDF]

Cureus
Toups CA, Guillot LG, Redondo K, Jensen S, Klein J, Marrero L.   +5 more
europepmc   +1 more source

Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma

Acta Ophthalmologica, Volume 104, Issue 2, Page 225-232, March 2026.
Abstract Purpose Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some patients progress despite significant IOP lowering, potentially due to impaired ocular blood flow. This study aimed to evaluate the effects of dronabinol, a synthetic tetrahydrocannabinol derivative, on ...
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Marihan Abensperg‐Traun, Liudmyla Petric, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Development of Carborane-Based Benzothiazole Analogues as Cannabinoid Receptor Type 2 (CB₂R) Ligands. [PDF]

ACS Omega
Ueberham L, Kazimir A, Deuther-Conrad W, Hey-Hawkins E.   +3 more
europepmc   +1 more source

Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor

Proceedings of the National Academy of Sciences of the United States of America, 2012
F. Pamplona, J. Ferreira, Octávio Menezes de Lima, F. S. Duarte, A. Bento, S. Forner, J. G. Villarinho, L. Bellocchio, C. Wotjak, Raissa Lerner, K. Monory, B. Lutz, C. Canetti, I. Matias, J. Calixto, G. Marsicano, M. Guimarães, R. Takahashi   +17 more
semanticscholar   +1 more source

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Fenebrutinib and Effect on the QT/QTc Interval in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Fenebrutinib is a Bruton's tyrosine kinase inhibitor under investigation for the treatment of multiple sclerosis. The goal of this study was to investigate the effect of fenebrutinib on cardiac repolarization (QT interval) as well as its safety, tolerability, and pharmacokinetics in healthy participants.
Yan Xu, Sonoko Kawakatsu, Denison Kuruvilla, John N. Ratchford, Qi Qi, Malgorzata Sierzega, Lin Pan, Jiajie Yu   +7 more
wiley   +1 more source

Neuroprotective effects of G9a inhibition and cannabinoid receptor activation in Alzheimer's disease through a pharmacological approach. [PDF]

Neurotherapeutics
Bellver-Sanchis A, Ribalta-Vilella M, Lillo J, Ortuño-Sahagún D, Franco R, Pallàs M, Navarro G, Griñán-Ferré C.   +7 more
europepmc   +1 more source

‘SASADECC’—A Unique Model of Collaborative Care Between Government and Non‐Government Health Services for Adolescents With Complex Substance Use Issues

Drug and Alcohol Review, Volume 45, Issue 3, March 2026.
ABSTRACT Introduction Despite the importance of early intervention, major treatment gaps exist for adolescents with substance use issues. This report describes a unique collaboration between government and non‐government health services—The Specialist Addiction Service for Adolescents (SASA) adolescent addiction psychiatry service and Sydney Drug ...
David E. A. Gordon, Belinda Volkov, Arezu Akbarian, Lauren A. Monds, Mark Montebello   +4 more
wiley   +1 more source

How THC works: Explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1. [PDF]

iScience
Shahbazi-Raz F, Meister D, Mohammadzadeh A, Trant JF.   +3 more
europepmc   +1 more source

Functional Selectivity in CB2 Cannabinoid Receptor Signaling and Regulation: Implications for the Therapeutic Potential of CB2 Ligands

Molecular Pharmacology, 2012
Brady K. Atwood, J. Wager-Miller, C. Haskins, A. Straiker, K. Mackie   +4 more
semanticscholar   +1 more source