Results 191 to 200 of about 74,377 (332)

Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3‐Way Crossover Trial

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 147-157, January 2026.
Cannabidiol (CBD) is approved as an adjunctive treatment of seizures associated with Dravet syndrome, Lennox–Gastaut Syndrome, and tuberous sclerosis. Its therapeutic and adverse effects are thought to arise, at least partly, from a pharmacokinetic interaction with clobazam, another anti‐seizure medication (ASM).
Andriy A. Gorbenko   +7 more
wiley   +1 more source

Synthesis and Pharmacological Characterization of a Novel Cannabinoid Receptor 1 Antagonist. [PDF]

open access: yesACS Omega
Bengoetxea de Tena I   +13 more
europepmc   +1 more source

HS‐FET‐GC/MS‐Method Development and Validation for Analysis of 45 Terpenes—Creating a Complementary Tool for Comprehensive Profiling of Cannabis Flowers in Forensics

open access: yesDrug Testing and Analysis, Volume 18, Issue 1, Page 118-138, January 2026.
Legalisation of medicinal cannabis leads to an increasing complexity of specific forensic questions. Terpenes, volatile hydrocarbons with modular construction principle of isoprene subunits, are suggested as second substance class alongside phytocannabinoids for classification of cannabis material.
Marica Hundertmark   +2 more
wiley   +1 more source

The cannabinoid CB1 receptor inverse agonist AM 251 and antagonist AM 4113 produce similar effects on the behavioral satiety sequence in rats

open access: green, 2008
Janel Hodge   +7 more
openalex   +1 more source

Astrocytic Chromatin Remodeler ATRX Gates Hippocampal Memory Consolidation Through Metabolic and Synaptic Regulation

open access: yesGlia, Volume 74, Issue 1, January 2026.
Astrocytic ATRX loss causes non‐cell‐autonomous neuronal hyperexcitability. Inducing ATRX deficiency in astrocytes causes selective long‐term memory deficits. Dynamic transcriptomic changes reveal metabolic and synaptic pathway dysregulation. ABSTRACT Astrocytes are increasingly recognized as active regulators of synaptic transmission and memory, yet ...
Miguel A. Pena‐Ortiz   +6 more
wiley   +1 more source

Cannabigerol Modulates Cannabinoid Receptor Type 2 Expression in the Spinal Dorsal Horn and Attenuates Neuropathic Pain Models. [PDF]

open access: yesPharmaceuticals (Basel)
Rezende B   +13 more
europepmc   +1 more source

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