Bidirectional Alterations of Hippocampal Cannabinoid 1 Receptors and Their Endogenous Ligands in a Rat Model of Alcohol Withdrawal and Dependence [PDF]
Somsak Mitrirattanakul +6 more
openalex +1 more source
Two small placebo‐controlled trials evaluated the effects of cannabidiol (CBD) in patients with alcohol use disorder (AUD), with and without co‐occurring post‐traumatic stress disorder (PTSD). CBD was rapidly absorbed and generally well tolerated in dosages of up to 1200 mg/day. Both treatment groups showed large reductions in drinking.
Michael P. Bogenschutz +6 more
wiley +1 more source
Kinin B1 receptor mediates acute cardiovascular and neural responses following cannabinoid receptor 1 activation in conscious male mice. [PDF]
Theobald D +3 more
europepmc +1 more source
Modulation of Pilocarpine-Induced Seizures by Cannabinoid Receptor 1
Rebecca L. Kow +5 more
openalex +2 more sources
Cannabinoid receptors in submandibular acinar cells: functional coupling between saliva fluid and electrolytes secretion and Ca2+ signalling [PDF]
Olga Kopach +5 more
openalex +1 more source
Neuroprotective effects of G9a inhibition and cannabinoid receptor activation in Alzheimer's disease through a pharmacological approach. [PDF]
Bellver-Sanchis A +7 more
europepmc +1 more source
Genotype–Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers
ABSTRACT Cannabidiol (CBD) use has increased in America due to its widespread availability. Cannabidiol is metabolized by multiple polymorphic enzymes including CYP3A, CYP2C9, and CYP2C19. We sought to evaluate the genotype‐specific adverse events and pharmacokinetic profiles of cannabidiol, 7‐OH cannabidiol (an active metabolite), and 7‐COOH ...
Jumar Etkins +11 more
wiley +1 more source
In vitro CB<sub>1</sub> receptor activity of halogenated indazole synthetic cannabinoid receptor agonists. [PDF]
Green H +9 more
europepmc +1 more source

