Results 31 to 40 of about 50,545 (304)

Cannabinoid Hyperemesis [PDF]

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2009
Cannabinoid hyperemesis syndrome is characterized by chronic, heavy use of cannabis, recurrent episodes of severe nausea and intractable vomiting, and abdominal pain. Temporary relief of symptoms is achieved by taking a hot bath or shower, and resolution of the problem when cannabis use is stopped.
openaire   +3 more sources

Cannabinoids in the Older Person: A Literature Review

open access: yesGeriatrics, 2020
Introduction: Medical cannabinoids have received significant mainstream media attention in recent times due to an evolving political and clinical landscape.
William Beedham   +4 more
doaj   +1 more source

Semi-quantitative analysis of cannabinoids in hemp (Cannabis sativa L.) using gas chromatography coupled to mass spectrometry

open access: yesJournal of Cannabis Research, 2022
Background Hemp (Cannabis sativa L.) is a producer of cannabinoids. These organic compounds are of increasing interest due to their potential applications in the medicinal field.
Luca De Prato   +6 more
doaj   +1 more source

Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis

open access: yesMolecules, 2021
Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during the early 19th century. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type ...
Mohamed M. Radwan   +3 more
doaj   +1 more source

The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. [PDF]

open access: yesPLoS ONE, 2010
Cannabinoids represent unique compounds for treating tumors, including astrocytomas. Whether CB(1) and CB(2) receptors mediate this therapeutic effect is unclear.We generated astrocytoma subclones that express set levels of CB(1) and CB(2), and found ...
Eiron Cudaback   +3 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

How Cannabinol Is Utilized in Japan, a Country with Strict Cannabis Regulations—Its Purposes, Medical Effects, Adverse Events, and Dependence

open access: yesIntegrative Medicine Reports
Introduction: Cannabinol (CBN) was discovered in 1896, but its commercial use did not take off until recently, and there have been few studies on its use, safety, and efficacy.
Yuji Masataka   +6 more
doaj   +1 more source

The current state and future perspectives of cannabinoids in cancer biology

open access: yesCancer Medicine, 2018
To date, cannabinoids have been allowed in the palliative medicine due to their analgesic and antiemetic effects, but increasing number of preclinical studies indicates their anticancer properties. Cannabinoids exhibit their action by a modulation of the
Paweł Śledziński   +3 more
doaj   +1 more source

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

open access: yesAdvanced Science, EarlyView.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei   +7 more
wiley   +1 more source

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