Results 11 to 20 of about 33,341 (304)

Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro [PDF]

Reproductive Biology and Endocrinology
Background Sperm capacitation is a prerequisite for natural or in vitro fertilization. After capacitation, sperm become hyperactivated and undergo an acrosome reaction, which helps them penetrate the oocyte.
Lijun Shan, Linmei Gao, Yuhao Chai, Kun Li, Jianmin Yu, Fei Liang, Jiangfeng Qin, Ya Ni, Peibei Sun   +8 more
doaj   +2 more sources

Bottom-up approach to deciphering the targets of the ubiquitin-proteasome system in porcine sperm capacitation [PDF]

Scientific Reports
Capacitation is an essential post-testicular maturation event endowing spermatozoa with fertilizing capacity within the female reproductive tract, significant for fertility, reproductive health, and contraception.
Michal Zigo, Jacob Netherton, Natálie Zelenková, Karl Kerns, Veronika Kraus, Pavla Postlerová, Mark Baker, Peter Sutovsky   +7 more
doaj   +2 more sources

Regulation of Sperm Capacitation and the Acrosome Reaction by PIP 2 and Actin Modulation

Asian Journal of Andrology, 2015
Actin polymerization and development of hyperactivated (HA) motility are two processes that take place during sperm capacitation. Actin polymerization occurs during capacitation and prior to the acrosome reaction, fast F-actin breakdown takes place.
Haim Breitbart, Maya Finkelstein
doaj   +2 more sources

NADPH Oxidase 5 and Melatonin: Involvement in Ram Sperm Capacitation

Frontiers in Cell and Developmental Biology, 2021
Reactive oxygen species (ROS) play an essential role in mammalian sperm capacitation. NADPH oxidase 5 (NOX5) has been described as the main source of ROS production in some mammalian spermatozoa, such as human and equine. On the other hand, melatonin can
Sara Miguel-Jiménez, Blanca Pina-Beltrán, Silvia Gimeno-Martos, Melissa Carvajal-Serna, Adriana Casao, Rosaura Pérez-Pe   +5 more
doaj   +1 more source

Between Equity and Differentiation: An Analytical schema of the social function of education

International Journal of Sociology of Education, 2013
The educational sphere has an internal function relatively agreed by social scientists. Nonetheless, the contribution that educational systems provide to the society (i.e., their social function) does not have the same degree of consensus.
Ignacio Madero Cabib, Cristobal Madero Cabib   +1 more
doaj   +1 more source

Essential role of CFTR in PKA-dependent phosphorylation, alkalinization, and hyperpolarization during human dperm capacitation [PDF]

, 2017
Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation.
Austin, Berger, Bobadilla, Buffone, Buffone, Buffone, Buffone, Chang, Chen, Chen, Chen, Chávez, Chávez, De Jonge, De La Vega-Beltran, Demarco, Diao, Dirami, Dostmann, Ellsworth, Escoffier, Esteves, Figueiras-Fierro, Gabriel, Gadsby, Hernández-González, Ishiguro, José, Kase, Kujala, Köhn, l'Hoste, Laemmli, Leclerc, Li, Lishko, Lochner, Luconi, López-González, Ma, Melis, Mortimer, Muanprasat, Navarrete, Neill, Nishigaki, Nolan, Okamura, Rode, Schulz, Sheppard, Sorum, Stival, Stival, Tabcharani, Tang, Towbin, Visconti, Visconti, Wennemuth, Wertheimer, Xu, Zeng, Zeng   +63 more
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The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm [PDF]

, 2016
Sperm capacitation is required for fertilization. At the molecular level, this process is associated with fast activation of protein kinase A. Downstream of this event, capacitating conditions lead to an increase in tyrosine phosphorylation. The identity
Alvau, Antonio, Battistone, Maria Agustina, Cuasnicu, Patricia Sara, Da Ros, Vanina Gabriela, Darszon, Alberto, De la Vega Beltran, José Luis, Gervasi, Maria Gracia, Greer, Peter, Krapf, Diego, Navarrete, Felipe A., Salicioni, Ana María, Sánchez Cárdenas, Claudia, Visconti, Pablo E., Xu, Xinran   +13 more
core   +1 more source

CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]

, 2009
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Ackermann, Frauke, Boekhoff, Ingrid, Borth, Heike, Buech, Thomas, Gudermann, Thomas, Zitranski, Nele   +5 more
core   +1 more source

Progesterone significantly enhances the mobility of boar spermatozoa [PDF]

, 2013
Progesterone released from the cumulus cells of the oocyte causes a number of physiological responses in human sperm cells including hyperactivation, acrosome reaction and chemotaxis. We employed a validated sperm mobility assay, which involves measuring
Adya, Ashok K., Brown, Sean G., Campbell, Johan M., Madamidola, Oladipo, Savage, Anne L., Soriano, Renalyn, Tamhane, Kshitij   +6 more
core   +3 more sources

Redox regulation of mammalian sperm capacitation

Asian Journal of Andrology, 2015
Capacitation is a series of morphological and metabolic changes necessary for the spermatozoon to achieve fertilizing ability. One of the earlier happenings during mammalian sperm capacitation is the production of reactive oxygen species (ROS) that will ...
Cristian O′Flaherty
doaj   +1 more source