Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation [PDF]
, 2005 The mechanisms involved in the regulation of mammalian sperm motility are not well understood. Calcium ions (Ca(2+)) have been suggested to play a key role in the maintenance of motility; nevertheless, how Ca(2+) modulates this process has not yet been ...
Buffone, Mariano Gabriel +6 more
core +1 more source
Influence of in vitro capacitation time on structural and functional human sperm parameters
Asian Journal of Andrology, 2020 A cascade of dramatic physiological events is linked to the sperm acrosome reaction and binding to the oocyte's zona pellucida during human sperm capacitation.
Paula Sáez-Espinosa +7 more
doaj +1 more source
Osteopontin enhances sperm capacitation and in vitro fertilization efficiency in boars
Journal of Animal Science and Technology, 2022 In this study, we used more reliable experimental materials and methods to detect the effects of osteopontin (OPN) on boar sperm in vitro capacitation, acrosome reaction, and fertilization efficiency.
Yun Chen, Kai Wang, Shouquan Zhang
doaj +1 more source
Capacitation promotes a shift in energy metabolism in murine sperm
Frontiers in Cell and Developmental Biology, 2022 In mammals, sperm acquire fertilization ability after a series of physiological and biochemical changes, collectively known as capacitation, that occur inside the female reproductive tract. In addition to other requirements, sperm bioenergetic metabolism
Maximiliano Tourmente +5 more
doaj +1 more source
Mammalian sperm capacitation: In vivo and in vitro juxtaposition
Veterinary Integrative Sciences, 2022 The development of assisted reproductive technologies (ART) in mammalian species such as in vitro embryo production (IVEP) has the potential to provide great benefits for significant population increase, improve genetic performance and ...
Haris Setiawan +4 more
doaj +1 more source
Human sperm ion channel (dys)function:implications for fertilization [PDF]
, 2019 BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R. +3 more
core +4 more sources
, 2012 The ejaculated semen consists of two major components viz. sperm cells (spermatozoa) and the fluid part obtained after centrifugation called seminal plasma.
P Perumal
core +2 more sources
Adhesion to oviduct glycans regulates porcine sperm Ca2+ influx and viability.
PLoS ONE, 2020 Before fertilization, sperm bind to epithelial cells of the oviduct isthmus to form a reservoir that regulates sperm viability and capacitation. The sperm reservoir maintains optimum fertility in species, like swine, in which semen deposition and ...
Sergio A Machado +4 more
doaj +1 more source
Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity [PDF]
, 2014 STUDY QUESTION: Can we identify compound(s) with reported phosphodiesterase inhibitor (PDEI) activity that could be added to human spermatozoa in vitro to enhance their motility without compromising other sperm functions?
Alasmari +54 more
core +5 more sources
Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF [PDF]
, 2016 STUDY QUESTION. Are significant abnormalities in outward (K+) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success?
Barratt, Christopher L. R. +9 more
core +6 more sources