Results 51 to 60 of about 815,985 (386)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Enhanced self-healing capacity in cementitious materials by use of encapsulated carbonate precipitating bacteria : from proof-of-concept to reality [PDF]

open access: yes, 2013
In this study, two bacteria-based self-healing systems were developed for the proof-of-concept and approach to a realistic self-healing. A self-healing system with glass capillaries and silica sol gel carried bacterial cells was first built.
De Belie, Nele   +2 more
core  

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]

open access: yes, 2017
T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Coles, Marc   +10 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Modeling of water rising in hydraulically coupled cylindrical capillaries of different radii

open access: yesAdvanced Engineering Research, 2018
Introduction. Vertical upward flow of water in the plant xylem occurs under the action of the water surface tension in the capillary menisci. In some papers, it is shown that the distribution of water in the inclined capillary systems is subject to the ...
I. A. Kipnis, Yu. M. Vernigorov
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

VEGF-A isoforms induce the expression of APLN in endothelial cells during human prenatal lung development

open access: yesFrontiers in Cell and Developmental Biology
IntroductionSingle-cell RNA-sequencing analyses have revealed the existence of two distinct capillary cell populations in the human lung: general capillary cells (CAP1) and alveolar capillary cells (CAP2). Studies in mouse have shown that the splicing of
Antony Hoarau   +9 more
doaj   +1 more source

Evidence of acute inflammation in the periodontal ligament subsequent to orthodontic tooth movement in rats

open access: yesAustralasian Orthodontic Journal, 1989
Experimental orthodontic tooth extrusion can result in red cell diapedesis through the PDL vascular wall. Diapedesis is an early sign of acute inflammation.
Cooper Stephanie M., Sims Milton R.
doaj   +1 more source

Curcumin reduces blood-nerve barrier abnormalities and cytotoxicity to endothelial cells and pericytes induced by cisplatin

open access: yesFolia Morphologica, 2023
BACKGROUND: Cisplatin is a platinum-based antineoplastic agent used to treat cancers of solid organs. Neuropathy is one of its major side effects, necessitating dose reduction or cessation.
P. Kobutree   +4 more
doaj   +1 more source

Focusing Capillary Optics for Use in Solution Small-Angle X-Ray Scattering

open access: yes, 2007
Measurements of the global conformation of macromolecules can be carried out using small-angle X-ray scattering (SAXS). Glass focusing capillaries, manufactured at the Cornell High Energy Synchrotron Source (CHESS), have been successfully employed for ...
Andresen, Kurt   +8 more
core   +1 more source

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