Results 61 to 70 of about 755,011 (350)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Curcumin reduces blood-nerve barrier abnormalities and cytotoxicity to endothelial cells and pericytes induced by cisplatin

Folia Morphologica, 2023
BACKGROUND: Cisplatin is a platinum-based antineoplastic agent used to treat cancers of solid organs. Neuropathy is one of its major side effects, necessitating dose reduction or cessation.
P. Kobutree, A. Tothonglor, A. Roumwong, D. Jindatip, S. Agthong   +4 more
doaj   +1 more source

On production and asymmetric focusing of flat electron beams using rectangular capillary discharge plasmas

, 2017
A method for the asymmetric focusing of electron bunches, based on the active plasma lensing technique is proposed. This method takes advantage of the strong inhomogeneous magnetic field generated inside the capillary discharge plasma to focus the ...
Bagdasarov, G. A., Barber, S. K., Bobrova, N. A., Boldarev, A. S., Bulanov, S. S., Bulanov, S. V., Esarey, E., Gasilov, V. A., Gonsalves, A. J., Kando, M., Korn, G., Leemans, W. P., Levato, T., Margarone, D., Olkhovskaya, O. G., Sasorov, P. V., Schroeder, C. B., van Tilborg, J.   +17 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A study of nailfold capillaroscopy in different morphological variants of psoriasis in a tertiary care hospital

Journal of Marine Medical Society
Background: Psoriasis is a chronic skin disease. Nailfold capillaroscopy (NFC) is a method to analyze nail changes in autoimmune disorders and is gaining popularity as a bedside tool for studying the capillaroscopic changes of psoriasis. Aim: The aim was
Parul Kamboj, Vineet Vij, G B Prashantha, Preema Sinha, Choudhary Sampoorna Raj, Nidheesh Mohan Janardnan   +5 more
doaj   +1 more source

Effect of adaptation duration to environmental conditions of the north on morphofunctional restructuring of capillary blood flow

Russian Open Medical Journal, 2022
Background — We studied blood microcirculation and features of capillary morphology in young men with various duration of adaptation to the environmental conditions of Northeast Russia (Magadan Oblast).
Inessa V. Averyanova, Sergei I. Vdovenko
doaj   +1 more source

Enhanced self-healing capacity in cementitious materials by use of encapsulated carbonate precipitating bacteria : from proof-of-concept to reality [PDF]

, 2013
In this study, two bacteria-based self-healing systems were developed for the proof-of-concept and approach to a realistic self-healing. A self-healing system with glass capillaries and silica sol gel carried bacterial cells was first built.
De Belie, Nele, Verstraete, Willy, Wang, Jianyun   +2 more
core  

Focusing Capillary Optics for Use in Solution Small-Angle X-Ray Scattering

, 2007
Measurements of the global conformation of macromolecules can be carried out using small-angle X-ray scattering (SAXS). Glass focusing capillaries, manufactured at the Cornell High Energy Synchrotron Source (CHESS), have been successfully employed for ...
Andresen, Kurt, Bilderback, Donald H., Cornaby, Sterling, Kwok, Lisa W., Lamb, Jessica S., Park, Hye Yoon, Pollack, Lois, Qiu, Xiangyun, Smilgies, Detlef-M.   +8 more
core   +1 more source

Photoinitiated polymerisation of monolithic stationary phases in polyimide coated capillaries using visible region LEDs [PDF]

, 2008
The spatially controlled synthesis of poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolithic stationary phases in polyimide coated fused silica capillaries by visible light induced radical polymerisation using a three-component initiator and a
Abele, Al-Bokari, Bandari, Beiler, Brett Paull, Brian Lawless, Chatterjee, Chen, Dasgupta, Dominik Heger, Dulay, Eeltink, Gould, Kabatc, McDermott, Michael C. Breadmore, Mirek Macka, Moschou, Murphy, Nie, Nie, Okanda, Petr Klán, Schuster, Silvija Abele, Svec, Throckmorton, Viklund, Zarah Walsh   +28 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source