Results 51 to 60 of about 642,458 (299)

double‐coated capillaries

, 2013
The performance of dynamic double-coated fused-silica capillaries with Polybrene and chondroitin sulfate A has been compared with uncoated fused-silica capillaries for the determination of recombinant human growth factor (somatropin) charge variants. The
Amini, Ahmad,, Ahmad Amini
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Combined Effect of Aerobic Exercise and Normobaric Hyperoxia on Skeletal Muscle Capillary and Mitochondrial Function in Diabetic Rats

Physiologia
Background/Objectives: The combined effects of aerobic exercise and normobaric hyperoxia exposure on skeletal muscle in diabetes mellitus (DM) remain unclear.
Issei Sugimoto, Yugo Kimura, Yasuyuki Umezaki, Hiromi Izawa, Takumi Saito, Sumika Ogawa, Atsunori Itagaki, Ikue Kondo, Tomohito Nunomura, Sangun Lee   +9 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Coupling of capillary RBC flow failure with neuronal depolarization [PDF]

, 2009
RBC (oxygen-carrier) behaviour in the cerebrocortical microvasculature during K^+^-induced cortical spreading depression (CSD) was examined in urethane-anesthetized male Wistar rats (n=10).
Miyuki Unekawa, Minoru Tomita, Haruki Toriumi, Norihiro Suzuki, Yutaka Tomita   +4 more
core  

Representative pattern of nailfold capillaries.

, 2022
Representative images of nailfold capillaries showing straight and long loops, twisted or bushy loops, and non-dense and small loops. Scale bars: 100 μm.
Yukiko T. Matsunaga (4629049), Shizuka Nakano (12878545), Tadaaki Nakajima (4509151), Akihiko Kikuchi (1579216)   +3 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

HISTOLOGICAL STUDY OF HUMAN PLACENTA WITH EMPHASIS ON CAPILLARIES AND SYNCYTIAL KNOTS OF TERMINAL VILLI

Pakistan Armed Forces Medical Journal, 2008
Objective: To study the light microscopic structure of human placenta from different regions. To determine the role of the placenta in nutrition of the human fetus.
Khadija Qamar, Liaqat Ali Minhas, Muhammad Yunus Khan   +2 more
doaj   +2 more sources

Effects of transient intravascular volume overload on endothelial glycocalyx thickness in healthy anesthetized cats

Frontiers in Veterinary Science
IntroductionPrevious studies suggest that the endothelial glycocalyx is damaged by volume overload. This study assessed the effects of transient intravascular volume overload on estimated endothelial glycocalyx thickness in healthy cats, using sidestream
Ivayla D. Yozova, Neroli Thomson, Mitsuhiro Irie, Rebecca Owen, John S. Munday   +4 more
doaj   +1 more source

Quantitative Research of Capillaries in Terminal Villi of Mature Placentae

Biomolecules & Biomedicine, 2010
Advanced maternal age is known to be a risk factor for placental dysfunctions. The most common obstetric complications among older women would be considered as follows: gestational diabetes; preeclampsia; placenta praevia; preterm premature rupture of ...
Zlata Žigić, Sergije Marković, Đurđica Grbeša, Suada Ramić, Almir Halilović   +4 more
doaj   +1 more source