Results 151 to 160 of about 249,247 (291)
Considerations for the Use of AAV‐based Gene Therapy in HIV‐Positive Individuals With Haemophilia
Haemophilia, EarlyView.ABSTRACT Introduction There is a high prevalence of human immunodeficiency virus (HIV) infection among the haemophilia community due to treatment in the 1970s and 1980s with contaminated clotting factor. Lifelong treatment regimens for haemophilia and HIV are burdensome alone and pose a particular challenge for individuals living with both conditions ...
Jürgen K. Rockstroh +5 more
wiley +1 more source
Toward a Functional Cure for Chronic Hepatitis B: Current Landscape and Future Directions in Japan
Hepatology Research, EarlyView.Hepatitis B is a viral liver infection that can become chronic, increasing the risk of developing liver cancer and liver failure. Because current treatments rarely cure these problems, researchers are now focusing on a functional cure in which the virus becomes undetectable in blood and stays that way, even after the treatment ends.
Yutaka Handa +2 more
wiley +1 more source
The impact of accumulating immune adaptation in circulating strains of HIV‐1
HIV Medicine, EarlyView.Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi +7 more
wiley +1 more source
Journal of Applied Entomology, EarlyView.ABSTRACT The use of insectary plants to provide alternative food and shelter resources for enhancing natural enemy activity has been established as a common practice in IPM. Candidate flowering plant species have been screened and evaluated for their contribution to enhance life parameters of beneficial insects.
Francesc Gómez Marco +6 more
wiley +1 more source
Journal of Fish Biology, EarlyView.Abstract In open marine aquaculture, rearing diverse fish species in adjacent net pens facilitates the waterborne spread of red sea bream iridovirus (RSIV). This study systematically evaluated the horizontal transmission dynamics of RSIV in black sea bream (BSB, Acanthopagrus schlegelii) and Japanese sea bass (JS, Lateolabrax japonicus) under immersion
Chae‐yeong Ji +5 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Spring viremia of carp virus (SVCV) is a contagious pathogen associated with significant mortality and economic losses in freshwater aquaculture. Although reverse transcription quantitative PCR (RT‐qPCR) enables rapid detection, it does not distinguish between infectious and non‐infectious viral particles, which may lead to overestimation of ...
Ha‐Jeong Son +9 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Formalin‐inactivated vaccines are widely employed as a primary preventive strategy against red sea bream iridoviral disease (RSIVD), which poses a substantial economic threat to the aquaculture of rock bream (Oplegnathus fasciatus). However, conventional quantitative PCR (qPCR) cannot differentiate infectious virions from noninfectious vaccine
Sung‐Bin Moon +8 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Carp edema virus (CEV) infects the common carp (Cyprinus carpio) and causes the lethal koi sleepy disease (KSD). Signs of KSD include respiratory, detoxification, and osmoregulatory difficulties. Salt treatment re‐equilibrates blood sodium levels and can save the fish. However, it is unclear whether these fish are immunized, remain chronically
Mikolaj Adamek +12 more
wiley +1 more source
Importin α1 contributes to Venezuelan equine encephalitis virus-induced cell death, but is not required for the capsid-mediated blockage of nucleocytoplasmic trafficking. [PDF]
Front MicrobiolJamiu AT +10 more
europepmc +1 more source