Results 161 to 170 of about 177,162 (260)

Distinct evolutionary patterns of endemic and emerging parvoviruses and the origin of a new pandemic virus. [PDF]

Proc Natl Acad Sci U S A
López-Astacio RA, Wasik BR, Lee H, Voorhees IEH, Weichert WS, Adu OF, Goodman LB, Hafenstein SL, Truyen U, Parrish CR.   +9 more
europepmc   +1 more source

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak, Michelle C. M. van Winden, Thomas V. Harwood, Rachel Neurath, Suzanne M. Kosina, Katherine B. Louie, Matthew B. Sullivan, Simon Roux, Karsten Zengler, Vivek K. Mutalik, Trent R. Northen   +10 more
wiley   +1 more source

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71. [PDF]

Sci Adv
Zhou D, Kotecha A, Kelly JT, Huang PN, Chen YY, Walter TS, Duyvesteyn HME, Owens RJ, Ho SY, Lin TY, Fry EE, Ren J, Huang KA, Stuart DI.   +13 more
europepmc   +1 more source

A Non‐Host Pathogen Elicitor Induces Blast Resistance Mediated by OsNAC78‐Pir7b Module in Rice

Plant, Cell &Environment, EarlyView.
ABSTRACT Plants exhibit broad‐spectrum and persistent resistance induced by non‐host pathogens. Previous studies have found that syringolin A secreted by Pseudomonas syringae pv. syringae can activate the expression of defense‐related gene Pir7b in non‐host rice, but the underlying mechanism remains ambiguous.
Yunjie Xie, Yuling Lai, Xingqian Wu, Xiangzhen Yu, Jingwen Wei, Mengge Chen, Yongsheng Zhu, Liping Chen, Hongguang Xie, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +11 more
wiley   +1 more source

Safety of Adeno-Associated Viral Vectors in Gene Therapy: Mechanisms of Toxicity, Clinical Risks, and Strategies for Their Minimization. [PDF]

Int J Mol Sci
Tsaregorodtseva TS, Radyukhina MA, Ayupova AI, Solovyeva VV, Sufianov AA, Sufianova GZ, Rizvanov AA.   +6 more
europepmc   +1 more source

Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly. [PDF]

Proc Natl Acad Sci U S A
Gupta M, Waltmann C, Renner N, Wang Y, James LC, Jacques DA, Böcking T, Voth GA.   +7 more
europepmc   +1 more source

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, EarlyView.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

HIV-1 uncoating location dictates sites of integration. [PDF]

Nat Commun
Burdick RC, Patro SC, Bare E, Siddiqui R, Delviks-Frankenberry KA, Nikolaitchik OA, Hughes SH, Wu X, Hu WS, Pathak VK.   +9 more
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Species barriers in AAV tropism: mechanisms, models, and emerging solutions for clinical translation. [PDF]

Acta Biochim Pol
Xu X.
europepmc   +1 more source