Results 181 to 190 of about 249,247 (291)

Assessing the Impact of Wastewater Flow Rates on SARS‐CoV‐2 RNA Detection: Insights for Environmental Surveillance and Policymaking

Environmental Quality Management, Volume 35, Issue 4, Summer 2026.
We meta‐analyzed 10 studies to assess whether influent flow rate affects SARS‐CoV‐2 RNA detection in wastewater treatment plants serving ≤60,000 inhabitants. The pooled odds ratio (2.08; 95% CI: 0.994–37; p = 0.053) showed no significant association between flow rate and detection probability.
André Felipe Bendix, Alex Batista Trentin, Deborah Catharine De Assis Leite, Betty Cristiane Kuhn, Felipe Beijamini, Simone Wendt, Flavia Regina Oliveira de Barros, Naiana Cristine Gabiatti, Juliana Morini Küpper Cardoso, Nédia de Castilhos Ghisi   +9 more
wiley   +1 more source

Dengue Virus Capsid Protein Interaction With Nucleic Acids

BioFactors, Volume 52, Issue 3, May/June 2026.
Binding of dengue virus capsid protein (DENV C) to ssDNA alters Trp fluorescence intensity, lifetime, and anisotropy, revealing structural rearrangements in the complex and suggesting a possible association with liquid–liquid phase separation (LLPS). ABSTRACT Dengue virus (DENV) transmission has greatly increased in the last decade, partly due to the ...
Nelly M. Silva, Ana S. Martins, Nina E. Karguth, Maria J. Sarmento, Francisco J. Enguita, Roland G. Huber, Ivo C. Martins, Nuno C. Santos   +7 more
wiley   +1 more source

Mechanistic insights into CAM-induced disruption of HBV capsids revealed by all-atom MD simulations. [PDF]

PLoS Pathog
Pérez-Segura C, Goh BC, Hadden-Perilla JA.   +2 more
europepmc   +1 more source

Transgenic Lepidopteran‐Pests‐Resistant and Herbicide‐Tolerant Cotton Through Transfer of Cry1Ab‐vip3Aa and Cp4‐epsps+bar Genes

Plant Biotechnology Journal, EarlyView.
Qi Mou, Jun Zhang, Zhanfeng Si, Shangkun Jin, Wanying Zhang, Tianzhen Zhang   +5 more
wiley   +1 more source

Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis

ChemistryEurope, Volume 4, Issue 5, May 2026.
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1. [PDF]

Adv Sci (Weinh)
Zhang Y, Liu Y, Yao Z, Lai H, Chen X, Wang Z, Bao Y, Li T, Zhou X, Chen X, Yang P.   +10 more
europepmc   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley, Joshua D. Bryant, Samuel Vrana, Karuppiah Chockalingam, Zhilei Chen   +4 more
wiley   +1 more source

Genome-based taxonomic classification of <i>Listeria</i> phage and diversity analysis of major capsid protein, receptor-binding protein and endolysin. [PDF]

Front Microbiol
Chen J, Zhou H, Liu L, Mao P, Li L, Xu X, Pu J, Yang J, Sun H, Luo X, Wang Y, Ye C.   +11 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

A Rationally Designed AAV9-DM Capsid with Minimal Liver Tropism. [PDF]

Cells
Nabakowski ZC, Jaramillo IC, Tanachaiwiwat P, Keeler GD.   +3 more
europepmc   +1 more source