Results 121 to 130 of about 1,705,592 (288)
Using computational approaches to study dengue virus capsid assembly
Computational and Mathematical Biophysics, 2019 Dengue viral capsid plays a significant role in viral life cycle of dengue, especially in vial genome protection and virus-cell fusion. Revealing mechanisms of the viral capsid protein assembly may lead to the discovery of anti-viral drugs that inhibit ...
Salas Gicela G Saucedo +7 more
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Nucleocapsid Assembly of Baculoviruses
Viruses, 2019 The baculovirus nucleocapsid is formed through a rod-like capsid encapsulating a genomic DNA molecule of 80~180 kbp. The viral capsid is a large oligomer composed of many copies of various protein subunits.
Shuling Zhao +3 more
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A Protein-Capsid-Based System for Cell Delivery of Selenocysteine
, 2018 Selenocysteine (Sec) has received a lot of attention as a potential anticancer drug. However, its broad cytotoxicity limits its therapeutic usefulness. Thus, Sec is an attractive candidate for targeted drug delivery.
Kenneth J. Woycechowsky (2054407) +4 more
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Characterization of HIV-1 capsid-binding host proteins during infection [PDF]
, 2021 The human immunodeficiency virus type 1 (HIV-1) capsid is an assembly of over 1,500 capsid (CA) monomers that encapsulates the viral RNA genome. After infection of the cell, this structure dissociates in a process termed uncoating to reveal the reverse ...
Boggs, Emerson Ailidh
core
Functional studies on the rotavirus non-structural proteins NSP5 and NSP6 [PDF]
The rotavirus replication cycle has not been fully characterised, one vital stage of virus replication involves large cytoplasmic occlusion bodies termed viroplasms.
Rainsford, Edward
core
Generation of enhanced gene delivery vectors by directed evolution of adeno-associated virus [PDF]
, 2006 Despite promising advance in the development of viral vectors based on AAV for human gene therapy, several major hurdles for a more general use remain.
Endell, Jan
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Gene Order of the Poliovirus Capsid Proteins [PDF]
Journal of Virology, 1972 Two methods were used to determine the genetic map of the poliovirus capsid proteins. The first method uses pactamycin, a drug which selectively inhibits the initiation of protein synthesis and causes a change in the relative amounts of capsid proteins synthesized. This differential effect on each of the capsid proteins is interpreted as indicating the
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The DNA Ejection Process in Bacteriophage λ [PDF]
, 2007 Bacteriophages have long served as model systems through which the nature of life may be explored. From a physical or mechanical point of view, phages are excellent examples of natural nanotechnology: they are nanometer-scale systems which depend ...
Grayson, Paul Daniel
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Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid.
, 2002 Bacteriophage PRD1 shares many structural and functional similarities with adenovirus. A major difference is the PRD1 internal membrane, which acts in concert with vertex proteins to translocate the phage genome into the host.
Huiskonen, JT +6 more
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Protein chainmail: catenated protein in viral capsids.
Cell, 1998 The capsid shells of bacteriophage HK97 and several other phages contain polypeptides that are covalently linked into complexes so large that they do not enter polyacrylamide gels after denaturation. The enormous apparent size of these protein complexes in HK97 derives from a novel protein topology.
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