Results 161 to 170 of about 832,259 (254)

CD73-targeted CAR-NK cell therapy displays potent antitumor activity and translational potential in relapsed/refractory lung adenocarcinoma. [PDF]

Biomark Res
Liu Q, Dong Q, Chen Y, Wang N, Zhuang D, Chen L, Ye Y, Huang S, Zhong W, Zhang WK, Xu T, Sun J, Liu H.   +12 more
europepmc   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source

Correction: Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial. [PDF]

Exp Hematol Oncol
Huang R, Wang X, Yan H, Tan X, Ma Y, Wang M, Han X, Liu J, Gao L, Gao L, Jing G, Zhang C, Wen Q, Zhang X.   +13 more
europepmc   +1 more source

Targeted therapies in pemphigus vulgaris: Emerging horizons beyond rituximab

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rituximab‐refractory pemphigus vulgaris is driven by B‐cell repopulation, plasma‐cell persistence, IgG4 autoantibodies and anti‐drug antibodies. This review evaluates five emerging targeted classes acting at successive steps of disease: next‐generation anti‐CD20 antibodies, DSG3‐CAAR T cells, BTK inhibitors, BAFF/APRIL inhibitors and FcRn antagonists ...
Rhea Ahuja, Dedee Murrell
wiley   +1 more source

Advancing CAR-NK cell therapy in solid tumors: Current landscape and future directions. [PDF]

Cell Rep Med
Manzar GS, Hasan MF, Moore M, Tiberti S, Osorio NP, Basar R, Daher M.   +6 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Correction: Next-generation CAR-NK cell therapy: engineering strategies, translational challenges, and future perspectives in cancer immunotherapy. [PDF]

Cancer Cell Int
Bakhtiari M, Nickho H, Mahmoudi M, Lavi Arab F, Hoseinzadeh A, Baharlou R.   +5 more
europepmc   +1 more source

Kalman Filter Learning, Bounded Rationality and Informational Consistency

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT We develop a behavioural New Keynesian model with rational (RE) and boundedly rational (BR) agents. The latter are anticipated utility learners and use simple heuristic rules to forecast aggregate variables exogenous to their micro‐environment.
Szabolcs Deák, Paul Levine, Joseph Pearlman, Bo Yang   +3 more
wiley   +1 more source

Gain-of-function enhancers optimize CAR-NK cell-based anti-cancer immunotherapy. [PDF]

Immunol Cell Biol
Wong E, Souza-Fonseca-Guimaraes F.
europepmc   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR-NK Therapeutic Strategies. [PDF]

Adv Sci (Weinh)
Kim D, Jo S, Jang IH, Kim YJ, Jung Y, Ahn J, Lim H, Lee JJ, Lee K, Kim TD, Park SA.   +10 more
europepmc   +1 more source