Results 171 to 180 of about 30,272 (291)

A Novel Crawling Robot Based on the Hexagonal Mesh Structure and Enhanced PID Control Strategy

Journal of Field Robotics, EarlyView.
ABSTRACT The locomotion of crawling robots is similar to that of caterpillars, relying on foot adhesion and body contraction to ensure flexible movement without compromising stability. However, most existing pneumatic soft crawling robots are incapable of simultaneously achieving forward, backward, turning, and climbing capabilities.
Meng Hongjun, Ren Yuke, Wei Jingtao, Zhang Shupeng, Zhang Wei   +4 more
wiley   +1 more source

DQN‐Guided Subset‐Induced OCSVM Kernel Approximation for Imbalanced Anomaly Detection

IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
Anomaly detection under limited normal data remains a fundamental challenge due to severe class imbalance and scarcity of anomalies. We propose a novel framework that reformulates support vector selection in One‐Class SVM as a sequential decision‐making problem.
Wenqian Yu, Jiaying Wu, Jinglu Hu
wiley   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Monitoring active osprey nests with drones is more time efficient and less disturbing than conventional methods

Wildlife Biology, EarlyView.
Drones are used to monitor bird nesting sites at less accessible locations, such as on cliffs, human infrastructure, or within the tree canopy. While there are a growing number of studies documenting avian behavioral responses to various drones, there is a continued need to monitor taxa‐specific responses to different drone models. We explored both the
Natasha K. Murphy, Jared A. Elmore, Melanie R. Boudreau, Brian S. Dorr, Scott A. Rush   +4 more
wiley   +1 more source

CAR-NK Engineering to Overcome TME Barriers. [PDF]

Cells
Islam F, Pupovac A, Boyd RL, Trounson AO.   +3 more
europepmc   +1 more source

A genetically informed cross‐lagged twin study of the longitudinal association between addiction‐related behaviors and obesity

Addiction, EarlyView.
Abstract Background and aims Addiction‐related behaviors, such as loss of control eating (LOC), cigarette smoking and alcohol consumption, have been associated with high body mass index (BMI). This study aimed to assess genetic and environmental contributions to these associations over time.
Baiyu Qi, Heather M. Highland, Mariaelisa Graff, Cynthia M. Bulik, Soo Hyun Rhee, Michael C. Stallings, John K. Hewitt, Daniel E. Gustavson, Chandra A. Reynolds, Kari E. North, Melissa A. Munn‐Chernoff   +10 more
wiley   +1 more source

Cortisol-resistant CAR-NK cells overcome steroid-induced immunosuppression in lung cancer. [PDF]

Signal Transduct Target Ther
Chakraborty S, Pramanik J, Alviter-Raymundo G, Ward CJ, Shaji SK, Yamashita-Kanemaru Y, Ali FAZ, Banik D, Zhang Z, Veiga-Villauriz C, Homer NZM, Simpson J, Laforest S, Tong S, Zhao Q, Roy J, Iqbal M, Morris AC, Chapman MA, Roychoudhuri R, Hussein H, Klenerman D, Saeb-Parsy K, Mahata B.   +23 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Harnessing the Power of CAR-NK Cells for Solid Tumors: Challenges, Innovations, and Future Frontiers in Immunotherapy. [PDF]

Cancer Commun (Lond)
An M, Yan J, Liu B, Liu Q.
europepmc   +1 more source