Results 191 to 200 of about 5,478,695 (241)
Cancer Medicine, Volume 15, Issue 11, November 2026.ABSTRACT Introduction Treatment decisions in older patients with mature B‐cell lymphoproliferative disorders (MBLD) are frequently guided by chronological age and comorbidity burden, although their ability to predict clinically relevant outcomes remains uncertain.
Kevin Nasrinfar +6 more
wiley +1 more source
Clinical &Translational Immunology, Volume 15, Issue 11, 2026.Abstract Objectives Viral infections are predominantly managed with conventional antiviral drugs, which, despite their efficacy, can cause toxicity and promote resistance. Cell‐based immunotherapies offer an alternative, but cytomegaloviruses (CMV) profoundly interfere with MHC class I antigen presentation, thereby impairing conventional virus‐specific
Sabrina Kübel +14 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang +8 more
wiley +1 more source
Immune Regulation by Regnase‐1 and Related Endoribonucleases
European Journal of Immunology, Volume 56, Issue 11, November 2026.Regnase‐1 couples immune signaling to stem‐loop‐mediated mRNA decay. Its biological output depends on cellular and tissue context, determining whether it restrains inflammation, maintains tissue homeostasis, or suppresses inflammation‐associated tumorigenesis.
Takuya Uehata, Osamu Takeuchi
wiley +1 more source
Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea
Glia, Volume 74, Issue 11, November 2026.Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson +13 more
wiley +1 more source
Lineage switch in childhood leukemia
HemaSphere, Volume 10, Issue 11, November 2026.Abstract Lineage switch (LS) is a rare but aggressive immunophenotypic transformation of acute leukemia associated with limited therapeutic options and poor clinical outcome. Although LS has been increasingly recognized in the era of CD19‐directed immunotherapies, its biological basis remains incompletely understood.
Katharina Daugs +3 more
wiley +1 more source
MedComm, Volume 7, Issue 11, November 2026.To characterize systemic immune features associated with disease activity, peripheral blood was collected from 32 active SLE patients, 30 stable SLE patients, and 35 healthy donors. Comprehensive immune profiling was performed using flow cytometry, immune repertoire sequencing, and bulk RNA sequencing.
Jingyi Wu +15 more
wiley +1 more source
Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies
MedComm, Volume 7, Issue 11, November 2026.Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang +4 more
wiley +1 more source
Liver Injury Repair and Regeneration: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 11, November 2026.This review outlines the spatiotemporal framework of liver injury repair and regeneration, orchestrated by molecular signaling, multicellular niche crosstalk, metabolic reprogramming, and interorgan communication. Post‑injury regenerative cascades (initiation, proliferation, termination) rely on crosstalk between hepatocytes, Kupffer cells, hepatic ...
Mingyue Pan +15 more
wiley +1 more source
Practical considerations for pathologists when selecting digital pathology systems: an ESDIP guide
The Journal of Pathology, Volume 270, Issue 3, Page 328-341, November 2026.Abstract The implementation of digital pathology (DP) has been reported across academic, public, and private laboratory settings, providing valuable insights into workflow transformation. However, comparatively little guidance exists on how DP systems should be evaluated prior to acquisition and deployment.
Diana Montezuma +9 more
wiley +1 more source