Results 41 to 50 of about 43,661 (255)
Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]
, 2011 Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin +4 more
core +1 more source
Allergology International, 2005 Background: The bronchodilating action of β-agonists depends on the tone of airway smooth muscle or on spasmogen. To estimate the precise intrinsic activity of β-agonists, relaxation responses should be examined on maximally contracted airway smooth ...
Yuichiro Kamikawa, Naomi Takayama
doaj +1 more source
Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]
, 2017 The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica +9 more
core +2 more sources
Regulation of CCK-induced ERK1/2 activation by PKC epsilon in rat pancreatic acinar cells
AIMS Molecular Science, 2017 The extracellular signal-regulated kinase ERK1/2 is activated in pancreatic acinar cells by cholecystokinin (CCK) and other secretagogues with this activation mediated primarily by protein kinase C (PKC).
Chenwei Li, John A. Williams
doaj +1 more source
From Synaptic Plasticity and Critical Periods to Social Behavior and Stress: Getting to, and Staying in, CA2. [PDF]
HippocampusABSTRACT Hippocampal Area CA2, with some exceptions, had long been neglected in in vivo studies, due largely to its small size, and in in vitro studies because of its general similarity to CA3 and CA1. Increasing evidence showing that CA2 was molecularly distinct led to the increased appreciation of CA2 as a separate region, and as such, that it likely
Dudek SM.
europepmc +2 more sources
Molecules and Cells, 2009 We studied the effect of carbachol on pacemaker currents in cultured interstitial cells of Cajal (ICC) from the mouse small intestine by muscarinic stimulation using a whole cell patch clamp technique and Ca2+-imaging.
K. So +8 more
semanticscholar +1 more source
Intracellular free sodium and potassium, post-carbachol hyperpolarization, and extracellular potassium-undershoot in rat sympathetic neurones [PDF]
, 1983 Double-barrelled ion-sensitive microelectrodes were used to record the free intracellular Na+- and K+-concentrations ([Na+]i, [K+]i) and to determine their relation to changes in membrane potential and extracellular K+ ([K+]e) in rat sympathetic ganglia.
Brown +15 more
core +1 more source
Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. [PDF]
PLoS ONE, 2013 The presence of autoantibodies in cancer has become relevant in recent years. We demonstrated that autoantibodies purified from the sera of breast cancer patients activate muscarinic acetylcholine receptors in tumor cells.
María Gabriela Lombardi +7 more
doaj +1 more source
Journal of Biological Chemistry, 1998 We have examined the role of tyrosine phosphorylation in regulation of calcium-dependent chloride secretion across T84 colonic epithelial cells. The calcium-mediated agonist carbachol (CCh, 100 microM) stimulated a time-dependent increase in tyrosine ...
S. Keely, J. Uribe, K. Barrett
semanticscholar +1 more source
Frontiers in Neuroscience, 2019 There is little information on either the transition state occurring between slow-wave sleep (SWS) and rapid eye movement (REM) sleep, as well as about its neurobiological bases.
Carlos Carrera-Cañas +2 more
doaj +1 more source