Results 91 to 100 of about 838,554 (221)

Distribution characteristics and genomic epidemiology of carbapenem-resistant Acinetobacter baumannii

Journal of Infection in Developing Countries
Introduction: Carbapenem-resistant Acinetobacter baumannii poses significant challenges in clinical settings due to rapid emergence and limited treatment options.
Ruixiang Luo, Jinpei Lu, Yu Nong, Hong Zhang, Minmin Tian, Yufeng Wang, Shan Huang, Nannan Dai, Yihua Wang   +8 more
doaj   +1 more source

Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections. [PDF]

Drugs
Carbapenem-resistant Acinetobacter baumannii has been associated with over three hundred thousand annual deaths globally. It is resistant to most available antibiotics and associated with high morbidity and mortality. No global consensus currently exists for treatment strategies that balance safety and efficacy because of heterogeneity of treatment ...
Iovleva A, Fowler VG, Doi Y.
europepmc   +3 more sources

Investigation of antimicrobial susceptibility patterns and frequency of bla OXA genes in carbapenem resistant Acinetobacter baumannii strains

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Bachground and Aim: Acinetobacter baumannii is one of the important caues of nosocomial infection. Resistance to antibiotics specially carbapenem antibiotics is on the increase which can be an alarming sign for healthcare managers and personnel.
Mohsen Moghadasi, Davood Kalantar-Neyestanaki, Morteza Karami-Zarandi, Hossein Ali Rahdar, Seyedesomaye Jasemi, Moammad Mehdi Feizabadi   +5 more
doaj  

Carbapenem Resistance in Acinetobacter baumannii: Mechanisms, Therapeutics, and Innovations

Microorganisms
The global rise of carbapenem-resistant Acinetobacter baumannii (CRAB) strains poses a critical challenge to healthcare systems due to limited therapeutic options and high mortality rates, especially in intensive care settings. This review explores the epidemiological landscape and molecular mechanisms driving carbapenem resistance, including the ...
Joyce de Souza, Helena Regina Salomé D’Espindula, Isabel de Farias Ribeiro, Geiziane Aparecida Gonçalves, Marcelo Pillonetto, Helisson Faoro   +5 more
openaire   +3 more sources

A Multicenter Study of Risk Factors and Outcome of Hospitalized Patients with Infections Due to Carbapenem-Resistant Acinetobacter Baumannii

, 2011
Risk factors and outcome in patients who acquire nosocomial infections due to carbapenem-resistant Acinetobacter baumannii (CRAB) are rarely investigated.
SHENG, WANG-HUEI;LIAO, CHUN-HSIN;YANG, LAUDERDALE TSAI-LING;KO, WEN-CHIEN;CHEN, YAO-SHEN;LIU, JIEN-WEI;LAU, YEU-JUN;LIU, KE-SUN;HSU, MENG- SHIUAN;CHANG, SHAN-CHWEN, 盛望徽;廖俊星;楊采菱;柯文謙;陳垚生;劉建衛;劉有增;劉克森;許孟璇;張上淳   +1 more
core   +1 more source

Repurposing a drug to punish carbapenem-resistant Acinetobacter baumannii

Proceedings of the National Academy of Sciences
The OXA β-lactamases in Acinetobacter baumannii represent a primary mechanism for resistance to the carbapenems, a class of antibiotics that represent a last line for treatment. In a screen of an U.S. Food and Drug Administration (FDA)-approved drug library, we identified fendiline, a calcium
Jennifer M. Colquhoun, Carter U. Brzezinski, Andrew Ji, Julianna Marotta, Franziska A. V. Elsen, Robert A. Bonomo, Kerrie L. May, Stephan A. Sieber, Marcin Grabowicz, William M. Wuest, Philip N. Rather   +10 more
openaire   +2 more sources

Comparative study of phenotypic and genotypic expression of virulence factors in colonizing and pathogenic carbapenem resistant Acinetobacter baumannii (CRAB)

BMC Microbiology
Abstract Carbapenem resistant Acinetobacter baumannii has evolved as the most troublesome microorganism with multiple virulence factors. Biofilm formation, porins, micronutrient capturing mechanism and quorum sensing, provide protection against ...
Swati Sharma, Kamal Singh, Ashish Chaurasiya, Tuhina Banerjee, Royana Singh, Ghanshyam Yadav, Ashok Kumar   +6 more
doaj   +1 more source

Risk factors for carbapenem-resistant Acinetobacter baumanii blood stream infections in a neonatal intensive care unit, Delhi, India

Journal of Infection in Developing Countries, 2014
Introduction: Carbapenem-resistant Acinetobacter baumannii (CRAB) infection is being increasingly observed and is associated with significant morbidity and mortality in newborns.
Ajay Kumar, Valinderjeet Singh Randhawa, Nilay Nirupam, Yogita Rai, Arvind Saili   +4 more
doaj   +1 more source

Dissemination of carbapenem-resistant Acinetobacter baumannii in patients with burn injuries

Journal of the Chinese Medical Association, 2017
Carbapenem-resistant Acinetobacter baumannii has emerged as an important cause of infection in burn patients. This study aimed to characterize the antimicrobial susceptibility pattern, determine the prevalence of oxacillinase and metallo-beta-lactamase (MBL) genes, and type the A. baumannii isolates obtained from burn patients.During a 1-year period, a
Shoja, Saeed, Moosavian, Mojtaba, Rostami, Soodabeh, Farahani, Abbas, Peymani, Amir, Ahmadi, Khadijeh, Ebrahimifard, Nasim   +6 more
openaire   +2 more sources

Genetic Relationship of Multi-Resistant Acinetobacter baumannii Isolates in Kingdom of Saudi Arabia

, 2018
In the last two decades, there has been a remarkable rise in the instances of nosocomial infections associated with antibiotic-resistant Acinetobacter baumannii.
Reem Aljindan, Nasreldin Elhadi
core   +1 more source