Results 71 to 80 of about 838,554 (221)

Spread of multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa clones in patients with ventilator-associated pneumonia in an adult intensive care unit at a university hospital

Brazilian Journal of Infectious Diseases, 2015
Background: In Brazil, ventilator-associated pneumonia (VAP) caused by carbapenem resistant Acinetobacter baumannii and Pseudomonas aeruginosa isolates are associated with significant mortality, morbidity and costs.
Sabrina Royer, Ana Luiza Souza Faria, Liliane Miyuki Seki, Thiago Pavoni Gomes Chagas, Paola Amaral de Campos, Deivid William da Fonseca Batistão, Marise Dutra Asensi, Paulo P. Gontijo Filho, Rosineide Marques Ribas   +8 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Core and variable components in prokaryotic genomes [PDF]

, 2011
Acinetobacter baumannii and Stenotrophomonas maltophilia are opportunistic pathogens responsable for several hospital-acquired infections. We performed Extensive comparative analyses were performed in silico to elucidate the cromosomal organization of ...
Rocco, Francesco
core   +1 more source

Molecular Identification and Antibiotic Resistance Profiles of Acinetobacter baumannii Isolated from Blood Cultures of ICU Patients in Duhok City, Iraq.

Zanin Journal of Science and Engineering
This study aimed to examine the molecular identification of Acinetobacter baumannii in blood samples and the rate of multidrug resistance among ICU patients in Duhok City. One hundred thirty blood specimens were collected from ICU patients.
Bushra Fadhel Ibrahim, Bland Husamuldeen Abdullah   +1 more
doaj   +1 more source

Antibacterial and Antibiofilm Activity of a Chemically Characterized Cinnamomum verum Bark Methanolic Extract Against Multidrug‐Resistant Bacteria: Preliminary Antibiotic–Interaction Screening and Exploratory Molecular Docking

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri, Sarra Elmsehli, Assia kenich, Mabrouk Horchani, Hanen Najjaa, Naima Najah, Hasan Aljohi, Mohammad Nasser Alkhrayef, Roberta Ascrizzi, Guido Flamini, Ibrahim O. Alanazi, Mozaniel Santana de Oliveira   +11 more
wiley   +1 more source

Antibacterial Therapy Options for Infections Caused by Carbapenem-Resistant Acinetobacter baumannii

Антибиотики и Химиотерапия
The review presents current treatment regimens for infections associated with carbapenem-resistant Acinetobacter baumannii, which are leading nosocomial pathogens exhibiting multidrug resistance to available antibacterial drugs. To date, widely used beta-
A. R. Goncharova, V. V. Gostev, N. E. Goncharov, O. S. Kalinogorskaya, N. S. Gladyshev   +4 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

A Lytic Bacteriophage Cocktail Attenuates Carbapenem‐Resistant Klebsiella pneumoniae–Acinetobacter baumannii Mixed‐Species Biofilms and Reshapes Transcriptional Responses

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
A lytic phage cocktail targeting CRKP–CRAB mixed biofilms was systematically evaluated through in vitro, device‐associated, and in vivo models. Integrated transcriptomic analysis revealed molecular responses underlying biofilm disruption, providing mechanistic insights and experimental evidence supporting phage cocktails as a promising strategy against
Xuefang Ren, Rui Zhu, Yijiang Yang, Xiaojuan You, Liuxiang Wang, Guangyu Fu, Yehuan Zheng, Chunxia Wang, Zhentao Wang, Yongwei Li   +9 more
wiley   +1 more source

[Carbapenem-resistant Acinetobacter baumannii strains].

Medycyna doswiadczalna i mikrobiologia, 2010
A. baumannii rods are opportunistic pathogens responsible generally for nosocomial infections. Resistance to carbapenems, observed among them, is a serious threat due to ability to be transmitted between bacterial species. The aim of our study was to evaluate the frequency of isolation and susceptibility to antibiotics of resistant to imipenem and/or ...
Tomasz, Bogiel, Joanna, Kwiecińska-Piróg, Katarzyna, Jachna-Sawicka, Eugenia, Gospodarek   +3 more
openaire   +1 more source

Treatment of infections caused by carbapenem-resistant Acinetobacter baumannii

Frontiers in Cellular and Infection Microbiology
Patients with severe carbapenem-resistant Acinetobacter baumannii (CRAB) infections currently face significant treatment challenges. When patients display signs of infection and the clinical suspicion of CRAB infections is high, appropriate treatment should be immediately provided. However, current treatment plans and clinical data for CRAB are limited.
Siqin Zhang, Lingfang Di, Yan Qi, Xiang Qian, Siwei Wang   +4 more
openaire   +3 more sources