Results 71 to 80 of about 896,879 (225)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han +4 more
wiley +1 more source
Carbapenem-resistant Acinetobacter baumannii is becoming increasingly prevalent in patients with diabetes mellitus in the Middle East. We examined the relationship of these bacteria and their resistance mechanisms to the diabetic disease status of ...
Benjamin A. Evans (3115968) +7 more
core +5 more sources
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair +3 more
wiley +1 more source
Moroccan Equisetum ramosissimum essential oil showed a distinct pulegone‐eudesmol‐rich profile and strain‐dependent antimicrobial activity, including against resistant isolates. The butanolic extract displayed stronger antioxidant activity in DPPH and β‐carotene bleaching assays, while docking suggested plausible interactions with selected microbial ...
Saida Sissi +7 more
wiley +1 more source
Carbapenem-Resistant Acinetobacter baumannii and Enterobacteriaceae in South and Southeast Asia [PDF]
SUMMARYCarbapenem-resistant Gram-negative bacteria, in particular theAcinetobacter baumannii-calcoaceticuscomplex andEnterobacteriaceae, are escalating global public health threats. We review the epidemiology and prevalence of these carbapenem-resistant Gram-negative bacteria among countries in South and Southeast Asia, where the rates of resistance ...
Li-Yang Hsu +5 more
openaire +2 more sources
Carbapenem-resistant Acinetobacter baumannii contamination in an intensive care unit
INTRODUCTION: Acinetobacter baumannii is a major pathogen causing infections in intensive care units (ICUs). In this study, we aimed to evaluate the presence of A.
Sílvia Dias de Oliveira (12696310) +3 more
core +1 more source
ABSTRACT Background and Aims A surge in antimicrobial resistance and multidrug‐resistant organisms among uropathogens have complicated its management over time. It is imperative to examine epidemiology and local antimicrobial susceptibility patterns to promote evidence‐based management.
Sanga Tenzin +7 more
wiley +1 more source
Investigation of the prevalence and role of mobile genetic elements associated with an aminoglycoside resistance gene, aacC2a, in Acinetobacter baumannii [PDF]
Includes abstract. Includes bibliographical references (leaves 115-141)
Jongwe, Tsungai Ivai
core +1 more source
Artificial Intelligence in Rapid Diagnostics for Antimicrobial Resistance: From Bench to Bedside
ABSTRACT Background Antimicrobial resistance (AMR) is one of the most urgent global public health threats, especially in low‐ and middle‐income countries. In 2019, bacterial AMR was estimated to have directly caused approximately 1.27 million deaths and to have been associated with 4.95 million deaths worldwide.
Nadine Mugisha +5 more
wiley +1 more source

