Results 51 to 60 of about 896,879 (225)

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis

Bacteria, 2022
Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of ...
Diego Lucas Neres Rodrigues, Francielly Morais Rodrigues da Costa, Wanderson Marques da Silva, Flavia Aburjaile, Vasco Azevedo   +4 more
openaire   +3 more sources

In vitro activity of tigecycline against multidrug resistant Acinetobacter baumannii [PDF]

, 2008
In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii Alessandro Capone1†, Silvia D’Arezzo1†, Paolo Visca1,2,*† and Nicola Petrosillo1† on behalf of the Gruppo Romano Acinetobacter baumannii 1National Institute for ...
S. DAREZZO, SANTINI, Claudio, P. VISCA, N. PETROSILLO, A. CAPONE, VISCA, PAOLO, null null, N. PETROSILLO ON BEHALF OF THE GRUPPO ROMANO ACINETOBACTER BAUMANNII, S. D'Arezzo   +8 more
core   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source

The global epidemiology of carbapenem-resistant Acinetobacter baumannii

JAC-Antimicrobial Resistance
Abstract Carbapenem-resistant Acinetobacter baumannii (CRAb) is a challenging, environmentally hardy organism with a propensity to spread within hospitals and a predilection to infect critically ill, vulnerable patients. With its potential for rapid transmission, limited treatment options, and substantial mortality, CRAb is recognized as
Angelique Boutzoukas, Yohei Doi
openaire   +2 more sources

Development and Application of a Rapid 23S rRNA‐Targeted Reverse Transcription Quantitative PCR System for the Detection and Quantification of Enterobacterales

Microbiology and Immunology, EarlyView.
ABSTRACT Bacteria belonging to the family Enterobacteriaceae occur as commensals or pathogens in humans. The increasing prevalence of multidrug‐resistant bacteria has raised global concern. Following the reclassification of Enterobacteriaceae species into the order Enterobacterales in 2016.
Satomi Atobe, Mai Hane, Akira Takahashi, Yukiko Kado, Rie Date, Shuta Yamamoto, Takashi Asahara   +6 more
wiley   +1 more source

Genotypic diversity among multidrug resistant Pseudomonas aeruginosa and Acinetobacter species at Mulago Hospital in Kampala, Uganda

BMC Research Notes, 2017
Background Multidrug resistant Pseudomonas aeruginosa and Acinetobacter species are common causes of nosocomial infections worldwide. Recently we reported the occurrence of carbapenem resistant Enterobacteriaceae, P.
David P. Kateete, Ritah Nakanjako, Moses Okee, Moses L. Joloba, Christine F. Najjuka   +4 more
doaj   +1 more source

Evolutionary and Epidemiological Characterization of Multidrug‐Resistant Escherichia coli Isolated From Pangolins in China

Integrative Zoology, EarlyView.
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang, Xue Wang, Jianan Zhao, Jun Zeng, Shijia Hu, Fang Ji, Guoying Dong, Hongxuan He, Chengmin Wang   +8 more
wiley   +1 more source

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in New Caledonia [PDF]

Clinical Microbiology and Infection, 2008
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) ranked third, with a frequency of 24.8%, among 202 strains of multidrug-resistant bacteria isolated from clinical samples in the main hospital of New Caledonia in 2004. All CR-Ab isolates were analysed by isoelectric focusing, conjugation, pulsed-field gel electrophoresis and PCR for the presence of ...
Le Hello, S., Falcot, V, Lacassin, F, Baumann, F, Nordmann, P, Naas, T   +5 more
openaire   +3 more sources

The transmission of nosocomial pathogens in an intensive care unit: a space–time clustering and structural equation modelling approach [PDF]

, 2009
We investigated the incidence of cases of nosocomial pathogens and risk factors in an intensive treatment unit ward to determine if the number of cases is dependent on location of patients and the colonization/infection history of the ward.
Sheridan, E. A., Rushton, Steven, Lanyon, Clare, O'Donnell, Anthony, Shirley, Mark, A. G. O'DONNELL, M. D. F. SHIRLEY, E. A. SHERIDAN, C. V. LANYON, S. P. RUSHTON   +9 more
core   +1 more source