Results 51 to 60 of about 25,429 (227)

Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections. [PDF]

Drugs
Carbapenem-resistant Acinetobacter baumannii has been associated with over three hundred thousand annual deaths globally. It is resistant to most available antibiotics and associated with high morbidity and mortality. No global consensus currently exists for treatment strategies that balance safety and efficacy because of heterogeneity of treatment ...
Iovleva A, Fowler VG, Doi Y.
europepmc   +3 more sources

The global epidemiology of carbapenem-resistant Acinetobacter baumannii

JAC-Antimicrobial Resistance
Abstract Carbapenem-resistant Acinetobacter baumannii (CRAb) is a challenging, environmentally hardy organism with a propensity to spread within hospitals and a predilection to infect critically ill, vulnerable patients. With its potential for rapid transmission, limited treatment options, and substantial mortality, CRAb is recognized as
Angelique Boutzoukas, Yohei Doi
openaire   +2 more sources

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in New Caledonia [PDF]

Clinical Microbiology and Infection, 2008
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) ranked third, with a frequency of 24.8%, among 202 strains of multidrug-resistant bacteria isolated from clinical samples in the main hospital of New Caledonia in 2004. All CR-Ab isolates were analysed by isoelectric focusing, conjugation, pulsed-field gel electrophoresis and PCR for the presence of ...
Le Hello, S., Falcot, V, Lacassin, F, Baumann, F, Nordmann, P, Naas, T   +5 more
openaire   +2 more sources

Semi-mechanistic PK/PD modelling of fosfomycin and sulbactam combination against carbapenem-resistant Acinetobacter baumannii.

, 2021
Due to limited treatment options for carbapenem-resistant Acinetobacter baumannii (CR-AB) infections, antibiotic combinations are now considered potential treatments for CR-AB.
Heffernan, AJ, Roberts, JA, Mohd Sazlly Lim, S, Sime, FB   +3 more
core   +1 more source

Antibiotic Resistance Profile of Wound Infection Isolates: High Resistance to Cephalosporins and Penicillin Among Ghanaian Patients in a Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aim Antibiotics remain among the most frequently prescribed medications in clinical practice. However, antimicrobial resistance (AMR) is an inevitable and irreversible consequence of bacterial adaptation to antimicrobial exposure.
Nelson Kwashie, Samuel Antwi‐Baffour, Lawrence Annison, Lydia Ofosua Appah, Uwakmfon Paul, Solomon Akpobi, Ebenezer Senu   +6 more
wiley   +1 more source

Clinical and Epidemiological Significance of Carbapenem Resistance in Acinetobacter baumannii Infections [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACT Carbapenems are considered the treatment of choice for Acinetobacter baumannii infections. Many facilities implement preventive measures toward only carbapenem-resistant A. baumannii (CRAB).
Ruthy, Tal-Jasper, David E, Katz, Nadav, Amrami, Dor, Ravid, Dori, Avivi, Ronit, Zaidenstein, Tsilia, Lazarovitch, Mor, Dadon, Keith S, Kaye, Dror, Marchaim   +9 more
openaire   +2 more sources

Heterocyclic Diaryliodonium-Based Inhibitors of Carbapenem-Resistant Acinetobacter baumannii

Microbiology Spectrum, 2023
Discovery of novel antibiotics targeting multidrug-resistant (MDR) pathogens such as A. baumannii is an urgent, unmet medical need. Our work has highlighted the potential of this unique scaffold to annihilate MDR A. baumannii alone and in combination with amikacin both in vitro
Pooja Kumari, Grace Kaul, T. Anand Kumar, Abdul Akhir, Manjulika Shukla, Suraj Sharma, Siddhesh S. Kamat, Sidharth Chopra, Harinath Chakrapani   +8 more
openaire   +2 more sources

β-lactamase genes in carbapenem resistance Acinetobacter baumannii isolates from a Turkish university hospital

Journal of Infection in Developing Countries, 2019
Introduction: The spread of Acinetobacter baumannii, resistant to most of the available antimicrobial agents, is a serious health problem. The high rate of carbapenem resistance among Acinetobacter baumannii isolates is considered as a threat to public ...
Umut Safiye Say Coskun, Emel Caliskan, Asegul Copur Cicek, Halbay Turumtay, Cemal Sandalli   +4 more
doaj   +1 more source

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Wastewater‐Based Assessment of Antimicrobial Resistance and Bacterial Communities in Urban and Rural Areas in the Province of Trento (Italy)

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Wastewater from urban and rural areas was analyzed to investigate antimicrobial‐resistant bacteria and resistance genes. ESBL‐Escherichia coli and genes coding for clinically relevant resistances, namely, those to macrolides, carbapenems, and vancomycin, were higher in urban than in rural areas.
Maya Petricciuolo, Agnese Carnevali, Alessia Torboli, Mattia Postinghel, Alessia Guasticchi, Paola Foladori, Maria Cadonna, Ermanno Federici   +7 more
wiley   +1 more source