Results 41 to 50 of about 838,554 (221)

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Genotypic diversity among multidrug resistant Pseudomonas aeruginosa and Acinetobacter species at Mulago Hospital in Kampala, Uganda

BMC Research Notes, 2017
Background Multidrug resistant Pseudomonas aeruginosa and Acinetobacter species are common causes of nosocomial infections worldwide. Recently we reported the occurrence of carbapenem resistant Enterobacteriaceae, P.
David P. Kateete, Ritah Nakanjako, Moses Okee, Moses L. Joloba, Christine F. Najjuka   +4 more
doaj   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in New Caledonia [PDF]

Clinical Microbiology and Infection, 2008
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) ranked third, with a frequency of 24.8%, among 202 strains of multidrug-resistant bacteria isolated from clinical samples in the main hospital of New Caledonia in 2004. All CR-Ab isolates were analysed by isoelectric focusing, conjugation, pulsed-field gel electrophoresis and PCR for the presence of ...
Le Hello, S., Falcot, V, Lacassin, F, Baumann, F, Nordmann, P, Naas, T   +5 more
openaire   +3 more sources

Molecular characterization and antibiotic resistance of Acinetobacter baumannii in cerebrospinal fluid and blood.

PLoS ONE, 2021
The increasing prevalence of carbapenem-resistant Acinetobacter baumannii (CRAB) caused nosocomial infections generate significant comorbidity and can cause death among patients. Current treatment options are limited.
Xiaohong Shi, Hong Wang, Xin Wang, Huaiqi Jing, Ran Duan, Shuai Qin, Dongyue Lv, Yufeng Fan, Zhenzhou Huang, Kyle Stirling, Lei Zhang, Jiazheng Wang   +11 more
doaj   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source

Antibacterial activity of enmetazobactam against Acinetobacter spp.: a molecular dissection of mechanism of action and resistance determinants

Antimicrobial Agents and Chemotherapy
The persistence of multidrug-resistant Acinetobacter baumannii remains a clinical challenge. Cefepime/enmetazobactam is a novel combination with demonstrated activity against extended-spectrum β-lactamase-producing Enterobacterales, but its activity ...
Gabriela-Alejandra Báez-Barroso, Arianna Rodríguez-Coello, Juan Carlos Vázquez-Ucha, Silvia López-Argüello, Michelle Outeda-García, Lucía González-Pinto, Andrea García-Pose, Paula Guijarro-Sánchez, Isaac Alonso-García, Emilio Lence, Concepción González-Bello, Antonio Oliver, Jorge Arca-Suárez, Bartolome Moya, Germán Bou, Alejandro Beceiro   +15 more
doaj   +1 more source

Evolutionary and Epidemiological Characterization of Multidrug‐Resistant Escherichia coli Isolated From Pangolins in China

Integrative Zoology, EarlyView.
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang, Xue Wang, Jianan Zhao, Jun Zeng, Shijia Hu, Fang Ji, Guoying Dong, Hongxuan He, Chengmin Wang   +8 more
wiley   +1 more source

Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward [PDF]

, 2016
We recently reported a dramatic increase in the prevalence of carbapenem-resistant Acinetobacter baumannii infections in the intensive care unit (ICU) of a Vietnamese hospital.
Phu Huong Lan, Nguyen, Schultz, Mark B, Edwards, David J, Ruth M Hall (1379481), Pham Thanh, Duy, David J Edwards (1379490), Tran Do Hoan, Nhu, Fournier-Level, Alexandre, Jane Hawkey (1112597), Schultz, Mark B., Holt, Kathryn E., Guy Thwaites (155694), Ingle, Danielle J., Thwaites, Guy, Mark Barry Schultz (1379496), Nhu, Nguyen Thi Khanh, Hall, Ruth M, Kathryn Elizabeth Holt (1379493), Kenyon, Johanna J, Thanh, Duy Pham, Hawkey, Jane, Ryan R Wick (1379499), Campbell, James I, Lan, Nguyen Phu Huong, Wick, Ryan R., Duy Pham Thanh (829799), Campbell, James I., Danielle J Ingle (1379478), Edwards, David J., Hoan, Nhu Tran Do, James I Campbell (1379487), Stephen Baker (30387), Alexandre Fournier-Level (654072), Holt, Kathryn E, Ingle, Danielle J, Wick, Ryan R, Hall, Ruth M., Johanna J Kenyon (1379475), Nguyen Phu Huong Lan (211394), Nguyen Thi Khanh Nhu (211342), Kenyon, Johanna J., Baker, Stephen, Nhu Tran Do Hoan (1379484), Thi Khanh Nhu, Nguyen   +43 more
core   +2 more sources

Discernment of Acinetobacter Species in World Scenario

Journal of Pure and Applied Microbiology, 2023
The morphology of Acinetobacter species is Gram-negative, nonmotile, nonfermenting, Strictly aerobic, Oxidase negative, and Catalase positive. It usually results from an infectious agent and is nonpathogenic in healthy people. A.
Nikita Meshram, Supriya Meshram
doaj   +1 more source