Results 31 to 40 of about 25,600 (227)

Carbapenem resistance in Acinetobacter baumannii: the molecular epidemic features of an emerging problem in health care facilities

Journal of Infection in Developing Countries, 2009
Acinetobacter baumannii is an opportunistic gram-negative pathogen with increasing relevance in a variety of nosocomial infections especially among intensive-care-unit (ICU) patients. Carbapenems have been widely used to treat serious multidrug-resistant
Raffaele Zarrilli, Maria Giannouli, Federica Tomasone, Maria Triassi, Athanassios Tsakris   +4 more
doaj   +1 more source

Semi-mechanistic PK/PD modelling of fosfomycin and sulbactam combination against carbapenem-resistant Acinetobacter baumannii. [PDF]

, 2021
Due to limited treatment options for carbapenem-resistant Acinetobacter baumannii (CR-AB) infections, antibiotic combinations are now considered potential treatments for CR-AB.
Heffernan, AJ, Roberts, JA, Mohd Sazlly Lim, S, Sime, FB   +3 more
core   +1 more source

Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter junii Conferred by Acquisition of blaOXA-24/40 and Genetic Characterization of the Transmission Mechanism between Acinetobacter Genomic Species

Microbiology Spectrum, 2022
Carbapenem resistance is increasing among Gram-negative bacteria, including the genus Acinetobacter. This study aimed to characterize, for the first time, the development of carbapenem resistance in clinical isolates of Acinetobacter junii and ...
Cristina Lasarte-Monterrubio, Paula Guijarro-Sánchez, Alba Bellés, Juan Carlos Vázquez-Ucha, Jorge Arca-Suárez, Carlos Fernández-Lozano, German Bou, Alejandro Beceiro   +7 more
doaj   +1 more source

Carbapenem-resistant Acinetobacter baumannii contamination in an intensive care unit [PDF]

, 2017
INTRODUCTION: Acinetobacter baumannii is a major pathogen causing infections in intensive care units (ICUs). In this study, we aimed to evaluate the presence of A.
Sílvia Dias de Oliveira (12696310), Otávio Hallal Ferreira Raro (9123344), Carlos Alexandre Sanchez Ferreira (12696307), Stephanie Wagner Gallo (12696304)   +3 more
core   +1 more source

Penicillin Binding Protein 7/8 Is a Potential Drug Target in Carbapenem-Resistant Acinetobacter baumannii [PDF]

, 2023
Limited therapeutic options dictate the need for new classes of antimicrobials active against carbapenem-resistant Acinetobacter baumannii. Presented data confirm and extend penicillin binding protein 7/8 (PBP 7/8) as a high-value target in the CR A ...
Mathur, P, Russo, TA, Davies, CJ, Adams, FG, Eijkelkamp, BA, Barnes, O, Hutson, A, Alvarado, CL, Ascari, A, Trivedi, G, Zang, M, Carlino-MacDonald, U   +11 more
core   +1 more source

Case report: Successful treatment of OXA-23 Acinetobacter baumannii neurosurgical infection and meningitis with sulbactam-durlobactam combination therapy

Frontiers in Medicine
Meningitis caused by Acinetobacter species is a rare complication of neurosurgical procedures, although it is associated with high morbidity and mortality.
Jacob W. Snowdin, Nicholas J. Mercuro, Michael P. Madaio, Stephen A. Rawlings   +3 more
doaj   +1 more source

Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis

Bacteria, 2022
Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of ...
Diego Lucas Neres Rodrigues, Francielly Morais Rodrigues da Costa, Wanderson Marques da Silva, Flavia Aburjaile, Vasco Azevedo   +4 more
openaire   +3 more sources

Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward [PDF]

, 2016
We recently reported a dramatic increase in the prevalence of carbapenem-resistant Acinetobacter baumannii infections in the intensive care unit (ICU) of a Vietnamese hospital.
Phu Huong Lan, Nguyen, Schultz, Mark B, Edwards, David J, Ruth M Hall (1379481), Pham Thanh, Duy, David J Edwards (1379490), Tran Do Hoan, Nhu, Fournier-Level, Alexandre, Jane Hawkey (1112597), Schultz, Mark B., Holt, Kathryn E., Guy Thwaites (155694), Ingle, Danielle J., Thwaites, Guy, Mark Barry Schultz (1379496), Nhu, Nguyen Thi Khanh, Hall, Ruth M, Kathryn Elizabeth Holt (1379493), Kenyon, Johanna J, Thanh, Duy Pham, Hawkey, Jane, Ryan R Wick (1379499), Campbell, James I, Lan, Nguyen Phu Huong, Wick, Ryan R., Duy Pham Thanh (829799), Campbell, James I., Danielle J Ingle (1379478), Edwards, David J., Hoan, Nhu Tran Do, James I Campbell (1379487), Stephen Baker (30387), Alexandre Fournier-Level (654072), Holt, Kathryn E, Ingle, Danielle J, Wick, Ryan R, Hall, Ruth M., Johanna J Kenyon (1379475), Nguyen Phu Huong Lan (211394), Nguyen Thi Khanh Nhu (211342), Kenyon, Johanna J., Baker, Stephen, Nhu Tran Do Hoan (1379484), Thi Khanh Nhu, Nguyen   +43 more
core   +1 more source

Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12 [PDF]

, 2015
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Wang, X, Zong, Z, Yang, Ping, Xie, Y, Zong, Zhiyong, Feng, Yu, Yang, P, Feng, Y, McNally, A, Wang, Xiaohui, McNally, Alan; id_orcid, Xie, Yi   +11 more
core   +1 more source

Molecular epidemiology and antimicrobial susceptibility of Pseudomonas spp. and Acinetobacter spp. from clinical samples at Jimma medical center, Ethiopia

Frontiers in Microbiology, 2022
IntroductionPseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii) can cause difficult-to-treat infections. We characterized molecular epidemiology of ceftazidime-resistant P. aeruginosa and carbapenem-resistant A. baumannii at
Tsegaye Sewunet, Daniel Asrat, Yimtubezinash Woldeamanuel, Abraham Aseffa, Christian G. Giske, Christian G. Giske   +5 more
doaj   +1 more source