Results 81 to 90 of about 25,429 (227)
Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen +4 more
wiley +1 more source
OXA beta-lactamase-mediated carbapenem resistance in Acinetobacter baumannii
Acinetobacter baumannii is a significant pathogen in health care settings. In recent years, an increase in carbapenem resistance among A. baumannii due to Ambler class B metallo-beta-lactamases or class D OXA carbapenamases has been reported. In this study we detected the presence of OXA carbapenamases and coproduction of metallo-beta-lactamases ...
Amudhan, S M. +3 more
openaire +2 more sources
Prediction of Antibiotic Influence by Presence of Some β-lactamase Gene in AcinetobacterInfected Patients Hospitalized in Tehran, Iran [PDF]
Acinetobacter baumannii which is gram-negative rod and infecting hospitalized patient often develops multiple drug resistance patterns and causes serious problem in treatment.
نیاکان, محمد +8 more
core
This study reveals that infections are highly prevalent in pediatric IEI patients after umbilical cord blood transplantation, with early‐stage infections and bloodstream infections strongly associated with poorer survival. These findings advocate for risk‐stratified surveillance and preemptive strategies in high‐risk subgroups.
Zhongling Wei +8 more
wiley +1 more source
Includes abstract. Includes bibliographical references (leaves 115-141)
Jongwe, Tsungai Ivai
core
Introduction: Carbapenem-resistant Acinetobacter baumannii poses significant challenges in clinical settings due to rapid emergence and limited treatment options.
Ruixiang Luo +8 more
doaj +1 more source
Mobile genetic elements related to carbapenem resistance in Acinetobacter baumannii
Acinetobacter baumannii is widely recognized as an important pathogen associated with nosocomial infections. The treatment of these infections is often difficult due to the acquisition of resistance genes. A. baumannii presents a high genetic plasticity which allows the accumulation of these resistance determinants leading to multidrug resistance.
Pagano, Mariana +2 more
openaire +4 more sources
Bachground and Aim: Acinetobacter baumannii is one of the important caues of nosocomial infection. Resistance to antibiotics specially carbapenem antibiotics is on the increase which can be an alarming sign for healthcare managers and personnel.
Mohsen Moghadasi +5 more
doaj
Repurposing a drug to punish carbapenem-resistant Acinetobacter baumannii
The OXA β-lactamases in Acinetobacter baumannii represent a primary mechanism for resistance to the carbapenems, a class of antibiotics that represent a last line for treatment. In a screen of an U.S. Food and Drug Administration (FDA)-approved drug library, we identified fendiline, a calcium channel blocker, had ...
Jennifer M. Colquhoun +10 more
openaire +2 more sources
A total of 81 clinical isolates of the three clinically important Acinetobacter spp., namely Acinetobacter baumannii , Acinetobacter genospecies 3 and Acinetobacter genospecies 13TU, were analysed for differences in carbapenem resistance genes. Of the 81
林鈺棋;盛望徽;陳宜君;張上淳;夏可强;李淑英 +1 more
core +1 more source

