Results 101 to 110 of about 42,101 (217)

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, Volume 13, Issue 21, 13 April 2026.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

OmpK36-mediated carbapenem resistance in Klebsiella pneumoniae

, 2022
Klebsiella pneumoniae (KP) is a common nosocomial pathogen that is frequently responsible for pneumonia, urinary tract infections and bacteraemia in patients with long term health challenges. Such infections can progress to sepsis, often necessitating intensive care support.
openaire   +2 more sources

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
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core   +4 more sources

Antimicrobial‐Resistance Genetic Markers Among Multidrug‐Resistant Enterobacteriaceae and Acinetobacter spp. From Vegetable Market Chains in Ethiopia

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Schematic overview of the study workflow explaining isolation of lactose‐fermenting Gram‐negative bacteria from farms and supermarkets, antimicrobial susceptibility testing, detection of resistance genes by PCR, and ERIC‐PCR to evaluate genetic diversity and relatedness among isolates.
Hemen Tesfaye, Adey Feleke Desta, Ahu Reis, Mine Egin, Osman Birol Ozgumus, Neslihan Akarsu, Mujib Abdulkadir, Haile Alemayehu, Tadesse Eguale, Ali Osman Kilic   +9 more
wiley   +1 more source

Emergence of KPC-producing Klebsiella pneumoniae in Italy [PDF]

, 2010
Background The emergence of KPC-producing K. pneumoniae has now become a global concern. KPC beta-lactamases are plasmid-borne and, like extended spectrum beta lactamases (ESBLs), can accumulate and transfer resistance determinants to other classes of ...
Fontana, C, Favaro, M, Sarmati, L, Natoli, S, Altieri, A, Bossa, M, Minelli, S, Leonardis, F, Favalli, C   +8 more
core   +2 more sources

Microbial Etiology and Antimicrobial Resistance in Pneumonia Among Hospitalized Patients in Kazakhstan: A Systematic Review and Single‐Arm Meta‐Analysis of Prevalence Data

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Pneumonia is an inflammatory condition of the lower respiratory tract, commonly caused by infection and associated with substantial morbidity and healthcare utilization. The burden of pneumonia on healthcare is exacerbated by limited data on pathogenic causes and associated antimicrobial resistance (AMR). Here, we conducted
Radmir Sarsenov, Maxim Solomadin, Alyona Lavrinenko, Vyacheslav Beloussov, Vitaliy Strochkov, Shynggys Orkara, Nurlan Sandybayev, Sergey Yegorov   +7 more
wiley   +1 more source

Spectrum of Pathogens and Their Resistance Profiles in Sputum and Pus Samples: A Retrospective Study From an Eastern Hospital of Nepal

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Respiratory and soft tissue infections remain major public health challenges both globally and in Nepal, increasingly complicated by rising antimicrobial resistance (AMR). The emergence of multidrug‐resistant (MDR) and extensively drug‐resistant (XDR) pathogens has made effective treatment more difficult, underscoring the ...
Rahi Bikram Thapa, Prakash Chandra Karkee, Sabin Shrestha   +2 more
wiley   +1 more source

Impact of COVID‐19 Pandemic on Antibiotic Resistance Patterns of Common Bacterial Pathogens to Antibiotics in Northern Ghana

Journal of Clinical Laboratory Analysis, Volume 40, Issue 7, April 2026.
This retrospective study analyzed and compared antimicrobial resistance patterns of common bacterial pathogens before (October 2018–March 2020) and during (April 2020–December 2022) the COVID‐19 pandemic in Ghana's Northern Region. Amoxiclav (p = 0.027), ceftazidime (p = 0.002), ciprofloxacin (p = 0.001), gentamycin (p = 0.035), and meropenem (p < 0 ...
Hisham Alhassan Osumanu, Oliver Nangkuu Deberu, Abass Abdul‐Karim, Ahmed Alhassan, Ebenezer Kojo Addae, Stephen Opoku Afriyie, Stebleson Azure, Sadia Alimatu Lawal, Daron Davies Agboyie, Valentine Cheba Koyiri, Hudu Yakubu, Enoch Weikem Weyori, Kennedy Mensah Osei, Benjamin Demah Nuertey, Godfred Acheampong   +14 more
wiley   +1 more source

EUropean prospective cohort study on Enterobacteriaceae showing REsistance to CArbapenems (EURECA): a protocol of a European multicentre observational study [PDF]

, 2017
Introduction: The rapid worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) constitutes a major challenge. The aim of the EUropean prospective cohort study on Enterobacteriaceae showing REsistance to CArbapenems (EURECA), which is part
Bravo Ferrer, José, Gutiérrez Gutiérrez, Belén, Pascual Hernández, Álvaro (Coordinador), Rodriguez Baño, Jesus, Sojo Dorado, Jesús   +4 more
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