Results 41 to 50 of about 59,922 (165)

Emergence of High-Level Cefiderocol Resistance in Carbapenem-Resistant Klebsiella pneumoniae from Bloodstream Infections in Patients with Hematologic Malignancies in China

Microbiology spectrum, 2022
Cefiderocol-resistant CRKP strains are emerging in bloodstream infections in Chinese patients with hematologic malignancies, although cefiderocol has not been approved for clinical use in China.
Peng Lan, Ye Lu, Zhong-Ju Chen, Xueqing Wu, X. Hua, Yan Jiang, Jian-Cang Zhou, Yun-Song Yu   +7 more
semanticscholar   +1 more source

CRISPR/Cas13-assisted carbapenem-resistant Klebsiella pneumoniae detection.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2023
BACKGROUND/PURPOSE Carbapenem-resistant Klebsiella pneumoniae (CRKP) is capable of causing serious community and hospital-acquired infections. However, currently, the identification of CRKP is complex and inefficient.
Ya-Ling Cao, Yuan Tian, Jing Huang, Ling Xu, Zi-Hao Fan, Zhen-Zhen Pan, Si-Si Chen, Yao Gao, Linlin Wei, Sujun Zheng, Xiang-Ying Zhang, Yan-Hua Yu, F. Ren   +12 more
semanticscholar   +1 more source

Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice

Communications Biology, 2022
Carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a severe global health challenge. We isolate and characterize two previously unidentified lytic phages, P24 and P39, with large burst sizes active against ST11 KL64, a major CRKP lineage ...
Qingqing Fang, Yu Feng, A. McNally, Z. Zong   +3 more
semanticscholar   +1 more source

Molecular characterization of KPC-2–positive Klebsiella pneumoniae isolates from a neurosurgical centre in Argentina

New Microbes and New Infections, 2018
Carbapenem-resistant Enterobacteriaceae is a growing concern worldwide. Klebsiella pneumoniae is an important nosocomial pathogen with a high capacity for nosocomial spread. We described the occurrence of plasmid-encoded KPC-2–harbouring K.
S. Montaña, M. Hernandez, J.S. Fernandez, M. Pennini, D. Centrón, A. Sucari, A. Iriarte, M.S. Ramírez   +7 more
doaj   +1 more source

Carbapenem-resistant Klebsiella pneumoniae capsular types, antibiotic resistance and virulence factors in China: a longitudinal, multi-centre study

Nature Microbiology
Epidemiological knowledge of circulating carbapenem-resistant Klebsiella pneumoniae (CRKP) is needed to develop effective strategies against this public health threat. Here we present a longitudinal analysis of 1,017 CRKP isolates recovered from patients
F. Hu, Yuqing Pan, Heng Li, Ren-Ru Han, Xiao Liu, Ruijing Ma, Yongqin Wu, Heyuan Lun, Xiao-Hua Qin, Jiayin Li, Aixi Wang, Min Zhou, Bing Liu, Zhe-Min Zhou, Ping He   +14 more
semanticscholar   +1 more source

Add-On Therapy with Ertapenem in Infections with Multidrug Resistant Gram-Negative Bacteria: Pediatric Experience

Case Reports in Infectious Diseases, 2017
Optimal therapy for infections with carbapenem resistant GNB is not well established due to the weakness of data. Patients presenting with bloodstream infections caused by multidrug resistant Klebsiella pneumoniae were treated with a combination ...
Sevgen Tanır Basaranoglu, Yasemin Ozsurekci, Kubra Aykac, Kamile Oktay Arıkan, Ayse Buyukcam, Ali Bulent Cengiz, Mehmet Ceyhan, Ates Kara   +7 more
doaj   +1 more source

Expansion and transmission dynamics of high risk carbapenem-resistant Klebsiella pneumoniae subclones in China: An epidemiological, spatial, genomic analysis.

Drug resistance updates
AIMS Carbapenem-resistant Klebsiella pneumonia (CRKP) is a global threat that varies by region. The global distribution, evolution, and clinical implications of the ST11 CRKP clone remain obscure.
Qi Wang, Ruo-Bing Wang, Shuyi Wang, Anru Zhang, Qiaoyan Duan, Shijun Sun, Long-Yang Jin, Xiao-Juan Wang, Ya-Wei Zhang, Chun-Lei Wang, Hai-Quan Kang, Zhi-Jie Zhang, K. Liao, Yinghui Guo, Liang Jin, Zhiwu Liu, Chun-Xia Yang, Hui Wang   +17 more
semanticscholar   +1 more source

Risk factors and mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection in a tertiary-care hospital in China: an eight-year retrospective study

Antimicrobial Resistance and Infection Control, 2022
Background The prevalence of carbapenem-resistant Klebsiella pneumoniae bloodstream infection (CRKP-BSI) is increasing worldwide. CRKP-BSI is associated with high rates of morbidity and mortality due to limited antibiotic choices.
Jie Chen, Huai-Lu Ma, Xiaoming Huang, Yanhui Cui, Wen-Zhong Peng, F. Zhu, Shiyang Ma, M. Rao, Peipei Zhang, Han Yang, Longxiang Su, R. Niu, P. Pan   +12 more
semanticscholar   +1 more source

Genomic Epidemiology and Characterization of Carbapenem-Resistant Klebsiella pneumoniae in ICU Inpatients in Henan Province, China: a Multicenter Cross-Sectional Study

Microbiology spectrum, 2023
In this study, we address the ongoing epidemic of carbapenem-resistant Klebsiella pneumoniae, a critical threat to public health. The alarming genotypic and phenotypic convergence of multidrug resistance and virulence highlights the increasingly ...
Shanmei Wang, Lei Wang, Jing Jin, Gang Li, Huan-Zhang Shao, Yang Song, Yuan-Zheng Sun, Yan Zhang, Jian-Jian Cheng, Li-Feng Li   +9 more
semanticscholar   +1 more source

Hypervirulent and carbapenem-resistant Klebsiella pneumoniae: A global public health threat.

Microbiology Research
The evolution of hypervirulent and carbapenem-resistant Klebsiella pneumoniae can be categorized into three main patterns: the evolution of KL1/KL2-hvKp strains into CR-hvKp, the evolution of carbapenem-resistant K. pneumoniae (CRKp) strains into hv-CRKp,
Ting-Yu Lei, Bin-Bin Liao, Liang Yang, Ying Wang, Xubing Chen   +4 more
semanticscholar   +1 more source