Results 171 to 180 of about 24,917 (198)

Carbapenemases: a worldwide threat

Expert Review of Anti-infective Therapy, 2013
β-lactam antibiotics remain one of our workhorse classes for serious infection due to their usually broad activity and attractive safety profile.
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Development and evaluation of the method for detecting metallo-carbapenemases among carbapenemase-producing Enterobacteriaceae

Journal of Microbiological Methods, 2019
A simple EDTA synergistic carbapenem inactivation method (esCIM) based on the simplified carbapenem inactivation method (sCIM) and EDTA synergistic carbapenem inactivation test (eCIM) detected the levels of metallo-β-lactamases (MBLs) carbapenemase.
Quanfeng, Liao, Yun, Xie, Chengcheng, Wang, Zhiyong, Zong, Siying, Wu, Ya, Liu, Weili, Zhang, Yi, Xie, Yuling, Xiao, Mei, Kang   +9 more
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Detection systems for carbapenemase gene identification should include the SME serine carbapenemase

International Journal of Antimicrobial Agents, 2013
Carbapenemase detection has become a major problem in hospitals that encounter outbreaks of infections caused by carbapenem-resistant Gram-negative bacteria. Rapid detection systems have been reported using multiplex PCR analyses and DNA microarray assays.
Karen, Bush, Megan, Pannell, John L, Lock, Anne Marie, Queenan, James H, Jorgensen, Ryan M, Lee, James S, Lewis, Deidre, Jarrett   +7 more
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Emerging carbapenemases: a global perspective

International Journal of Antimicrobial Agents, 2010
The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of this general increase is the unbridled dissemination of carbapenem resistance genes, namely KPC, OXA and metallo-β-lactamase variants.
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Carbapenemases: a problem in waiting?

Current Opinion in Microbiology, 2000
Carbapenems are stable to most prevalent beta-lactamases, and chromosomal carbapenemases are restricted to Stenotrophomonas maltophilia, to a few Bacteroides fragilis, and to rare pathogens. Nevertheless, an acquired metallo-beta-lactamase called IMP-1 is beginning to emerge in Pseudomonas aeruginosa and Enterobacteriaceae isolates in Japan, and has ...
D M, Livermore, N, Woodford
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Clinically significant carbapenemases: an update

Current Opinion in Infectious Diseases, 2008
To provide a brief synopsis of studies which have extended our understanding of carbapenem resistance in clinical isolates in terms of epidemiology, mechanism of action and genetic factors affecting their carriage and spread.Studies published in the last 18 months continue to confirm that VIM-2 is the dominant metallo-beta-lactamase in Pseudomonas ...
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Characterization of Klebsiella pneumoniae Coproducing KPC and NDM-1 Carbapenemases from Turkey

Microbial Drug Resistance, 2020
Aims: The emergence of multidrug-resistant and carbapenem-resistant Klebsiella pneumoniae has became a major public health threat. In this study, we describe the characteristics of isolates coproducing KPC and NDM-1 carbapenemases from patients ...
A. Tekeli, İ. Dolapçı, Ebru Evren, Elif Oğuzman, Z. C. Karahan   +4 more
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[Carbapenemases in enterobacteriaceae].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2011
Carbapenem-hydrolyzing beta-lactamases are the most powerful mechanism of resistance to carbapenems. Carbapenemases have been reported extensively worldwide now in Enterobacteriaceae. Carbapenemases of the KPC type have been reported first from the USA in Klebsiella pneumoniae, then worldwide with a marked endemicity in Israel and Greece.
P, Nordmann, A, Carrer
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[Carbapenemases in Pseudomonas spp].

Enfermedades infecciosas y microbiologia clinica, 2010
Pseudomonas aeruginosa is one of the most relevant nosocomial pathogens, as well as one of the main causes of chronic respiratory infections in patients with underlying diseases such as cystic fibrosis or chronic obstructive pulmonary disease. The high intrinsic antibiotic resistance of this pathogen, together with its extraordinary capacity for ...
Carlos, Juan Nicolau, Antonio, Oliver
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Klebsiella pneumoniae ST147: and then there were three carbapenemases

European Journal of Clinical Microbiology and Infectious Diseases, 2022
L. Mataseje, L. Chen, G. Peirano, K. Fakharuddin, B. Kreiswith, M. Mulvey, J. Pitout   +6 more
semanticscholar   +1 more source