Results 41 to 50 of about 19,967 (214)

The Burden of Antimicrobial‐Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Erfaneh Jafari, Babak Pourakbari, Mohammad Reza Asadi Karam, Reza Azizian, Mohammad Reza Modaresi, Setareh Mamishi   +5 more
wiley   +1 more source

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii from Southern Brazil

Revista de Epidemiologia e Controle de Infecção, 2021
Carbapenem resistance in Acinetobacter baumannii has reached extremely high levels worldwide and class D OXA-type carbapenemases are the main associated mechanism.
Gabriel de Paula Gollino, Bruna Machado Escobar, Ilson Dias da Silveira, Rosa Helena Robales Siqueira, Joseane Cristina Ferreira, Ana Lúcia da Costa Darini, Vanessa Bley Ribeiro   +6 more
doaj   +1 more source

Rapid Typing of Extended‐Spectrum β‐Lactamase (ESBL)‐ and Metallo‐β‐Lactamase (MBL)‐Producing Enterobacterales Using Fourier Transform Infrared (FT‐IR) Spectroscopy

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Clinical isolates of Klebsiella pneumoniae and Enterobacter cloacae complex were analyzed using FT‐IR spectroscopy and genotyping methods. High concordance was observed, demonstrating the potential of FT‐IR spectroscopy as a rapid screening tool.
Yasuhide Kawamoto, Kosuke Kosai, Mika Murata, Kenji Ota, Fujiko Mitsumoto‐Kaseida, Norihito Kaku, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara   +9 more
wiley   +1 more source

What do We Know so Far about Ges Carbapenemases, and What Threat do They Pose?

Postępy Mikrobiologii
Carbapenemases, classified as bacterial enzymes, have the ability to hydrolyze carbapenems – important broad-spectrum antibiotics. This work attempts to summarize the information on the diversity of Guiana Extended-Spectrum (GES) subgroup of ...
Rutkowski Kamil, Osnytskyy Anton, Ślifierska Magdalena, Jarząbek Paulina, Bielec Filip, Pastuszak-Lewandoska Dorota, Brauncajs Małgorzata   +6 more
doaj   +1 more source

Carbapenemases: Partners in crime

Journal of Global Antimicrobial Resistance, 2013
Carbapenemases, β-lactamases that inactivate carbapenems and most β-lactam antibiotics, are most widely known for their ability to confer resistance to β-lactams. They include serine carbapenemases, such as the widespread KPC family of enzymes, and the metallo-β-lactamases that contain the IMP, NDM and VIM enzyme families acquired by Gram-negative ...
openaire   +2 more sources

Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter

Advanced Science, Volume 13, Issue 3, 14 January 2026.
By altering the quantity and chemical composition of polyethylene‐derived dissolved organic matter, plastic color dynamically regulates bacterial metabolic interactions, thereby reshaping community resistance expression and facilitating the dissemination of antibiotic resistance.
Shuting Fang, Shuqin Liu, Jingui Huang, Yiquan Huang, Chao Chen, Qijun Ruan, Pengran Guo, Gangfeng Ouyang   +7 more
wiley   +1 more source

Epidemiology and Genetic Traits of Carbapenemase-Producing Enterobacterales: A Global Threat to Human Health

Antibiotics
Carbapenemase-producing Enterobacterales (CPE) represent an important threat to global health, resulting in an urgent issue in clinical settings. CPE often exhibit a multidrug-resistant (MDR) phenotype, thus reducing the antimicrobial armamentarium, with
Gualtiero Alvisi, Antonio Curtoni, Rossella Fonnesu, Aurora Piazza, Caterina Signoretto, Giorgia Piccinini, Davide Sassera, Paolo Gaibani   +7 more
doaj   +1 more source

Intra- and Extra-Hospital Dissemination of IMP-22-Producing Klebsiella pneumoniae in Northern Portugal: The Breach of the Hospital Frontier Toward the Community

Frontiers in Microbiology, 2021
The emergence of infections (and colonization) with Enterobacteriaceae-producing carbapenemases is a threatening public health problem. In the last decades, we watched an isolated case becoming a brutal outbreak, a sporadic description becoming an ...
Daniela Gonçalves, Daniela Gonçalves, Daniela Gonçalves, Daniela Gonçalves, Pedro Cecílio, Alberta Faustino, Carmen Iglesias, Fernando Branca, Alexandra Estrada, Helena Ferreira, Helena Ferreira   +10 more
doaj   +1 more source

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 235-244, January 2026.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu, Rachael M. Harrower, Ziang Li, Angela C. Brown   +3 more
wiley   +1 more source

Global emergence of double and multi-carbapenemase producing organisms: epidemiology, clinical significance, and evolutionary benefits on antimicrobial resistance and virulence

Microbiology Spectrum
Redundant carbapenemase-producing (RCP) bacteria, which carry double or multiple carbapenemases, represent a new and concerning phenomenon. The objective of this study is to conduct a comprehensive analysis of the epidemiology and genetic mechanisms of ...
Pei-Bo Yuan, Li-Ting Dai, Qi-Ke Zhang, Yu-Xia Zhong, Wan-Ting Liu, Ling Yang, Ding-Qiang Chen   +6 more
doaj   +1 more source