An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides [PDF]
Molecules, 2015 Oligosaccharide structures derived from the lipooligosaccharide of M. catarrhalis show that the highly branched glucose-rich inner core of the oligosaccharide has an altered conformation compared to the most truncated tetra-glucose-Kdo lgt1/4Δ ...
Martin Frank +4 more
doaj +8 more sources
Solvent interactions determine carbohydrate conformation [PDF]
Proceedings of the National Academy of Sciences, 2001 The relationship between the three-dimensional structures of oligosaccharides and polysaccharides and their biological properties has been the focus of many recent studies. The overall conformation of an oligosaccharide depends primarily on the orientation of the torsion angles (φ, ψ, and ω) between glycosyl residues. Numerous experimental
Karl N. Kirschner, Robert J. Woods
semanticscholar +5 more sources
The Role of Carbohydrate in Maintaining Extensin in an Extended Conformation [PDF]
Plant Physiology, 1986 Monomers of the plant cell wall glycoprotein extensin are secreted into the wall where they become cross-linked to each other to form a rigid matrix. Expression of the extensin matrix is correlated with the inhibition of further cell elongation during normal development, with increased resistance to virulent pathogens and with other physiological ...
L. Andrew Staehelin, Joel P. Stafstrom
semanticscholar +6 more sources
Gene-Silencing-Induced Changes in Carbohydrate Conformation in Relation to Bioenergy Value and Carbohydrate Subfractions in Modeled Plant (Medicago sativa) with Down-Regulation of HB12 and TT8 Transcription Factors. [PDF]
Int J Mol Sci, 2016 Gene silencing with RNA interference (RNAi) technology may be capable of modifying internal structure at a molecular level. This structural modification could affect biofunctions in terms of biodegradation, biochemical metabolism, and bioactive compound ...
Li X, Hannoufa A, Zhang Y, Yu P.
europepmc +4 more sources
Carbohydrate- and Conformation-dependent Cargo Capture for ER-Exit [PDF]
Molecular Biology of the Cell, 2005 Some secretory proteins leave the endoplasmic reticulum (ER) by a receptor-mediated cargo capture mechanism, but the signals required for the cargo-receptor interaction are largely unknown. Here, we describe a novel targeting motif that is composed of a high-mannose type oligosaccharide intimately associated with a surface-exposed peptide β-hairpin ...
Appenzeller-Herzog, C. +5 more
semanticscholar +7 more sources
Conformation of the Oligosaccharide Chain of GM1 Ganglioside in a Carbohydrate-Enriched Surface [PDF]
Biophysical Journal, 1998 The solution structure of ganglioside G(M1) carbohydrate moiety at the surface of a 102-kDa lipid-modified-G(M1) micelle is investigated by high-resolution 1H-NMR in H2O. The micellar surface can be considered a cluster-like lateral distribution of the gangliosides, each single monomer being anchored in a carbohydrate-enriched model membrane matrix. 1H
P. Brocca, P. Berthault, S. Sonnino
semanticscholar +6 more sources
Shape: automatic conformation prediction of carbohydrates using a genetic algorithm [PDF]
Journal of Cheminformatics, 2009 Background Detailed experimental three dimensional structures of carbohydrates are often difficult to acquire. Molecular modelling and computational conformation prediction are therefore commonly used tools for three dimensional structure studies ...
Rosen Jimmy +2 more
doaj +7 more sources
Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation [PDF]
Beilstein Journal of Organic Chemistry, 2014 Carbohydrate recognition is essential in cellular interactions and biological processes. It is characterized by structural diversity, multivalency and cooperative effects.
Nitin J. Pawar +4 more
doaj +2 more sources
Carbohydrate Self‐Assembly at Surfaces: STM Imaging of Sucrose Conformation and Ordering on Cu(100) [PDF]
Angewandte Chemie, 2019 Saccharides are ubiquitous biomolecules, but little is known about their interaction with, and assembly at, surfaces. By combining preparative mass spectrometry with scanning tunneling microscopy, we have been able to address the conformation and self ...
Sabine Abb +7 more
semanticscholar +4 more sources
Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL. [PDF]
PLoS ONE, 2017 Protein-carbohydrate interactions are very often mediated by the stacking CH-π interactions involving the side chains of aromatic amino acids such as tryptophan (Trp), tyrosine (Tyr) or phenylalanine (Phe).
Josef Houser +6 more
doaj +2 more sources