Results 51 to 60 of about 383,493 (318)

Dietary carbohydrate digestion and fermentation: Relevance for prevention of type 2 diabetes [PDF]

open access: yes, 2010
Dietary carbohydrate consumption has been related to the prevention of type 2 diabetes (T2DM). The fermentation process of non-digestible carbohydrates was thought to play a role through its fermentation products short-chain fatty acids (SCFAs).
Wang, Hongwei,, Wang, Hongwei
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Effects of wheat cultivar and harvest year on technological quality studied by univariate and multivariate analyses

open access: yesCzech Journal of Food Sciences, 2007
The effects of wheat cultivar and harvest year on the wheat technological quality were studied by univariate and multivariate statistical methods. Two wheat varieties sown in the harvest years 2003-2005 were used, the first one of European (cultivar ...
Ivan Švec   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Towards an Artificial Carbohydrates Supply on Earth

open access: yes, 2019
How to feed a growing global population in a secure and sustainable way? The conventional, biogenic agriculture has yet failed to provide a reliable concept which circumvents its severe environmental externalities—such as the massive use of land area ...
Florian Dinger (7355285)   +3 more
core   +1 more source

Gastric Emptying of Maltodextrin versus Phytoglycogen Carbohydrate Solutions in Healthy Volunteers: A Quasi-Experimental Study

open access: yes, 2022
Preoperative carbohydrate beverages have been shown to be beneficial in improving patient outcomes. There have been several investigations into the safety of maltodextrin as a preoperative carbohydrate.
Leila R. D. Hammond   +7 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Chemometrics of Wheat Composites with Hemp, Teff, and Chia Flour: Comparison of Rheological Features

open access: yesInternational Journal of Food Science, 2013
The mixolab, a rheological device developed recently, combines approved farinograph and amylograph test procedures. Analysing wheat flour composites with hemp, teff, or chia in terms of all three mentioned rheological methods, correspondence of ...
Marie Hrušková   +2 more
doaj   +1 more source

Application of amylographic method for determination of the staling of bakery products

open access: yesCzech Journal of Food Sciences, 2015
Staling is the general term that describes the time-dependent loss in quality of flavour and texture of bakery products after their baking and during storage.
Marcela Sluková   +3 more
doaj   +1 more source

The Important Roles Played in Substrate Binding of Aromatic Amino Acids in Exo-Inulinase From Kluyveromyces cicerisporus CBS 4857

open access: yesFrontiers in Molecular Biosciences, 2020
Inulinase is a member of the glycoside hydrolase family 32 (GH32). It catalyzes the randomly hydrolyzation of 2,1-β-D-fructosidic linkages in inulin and plays a role in the production of high-fructose syrup. In this study, detailed roles of the conserved
Junyan Ma   +6 more
doaj   +1 more source

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