Results 191 to 200 of about 13,653 (252)
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Pharmacokinetics of the β-carboline norharman in man
Life Sciences, 2001In healthy subjects, pharmacokinetics were characterised using single oral and sublingual administrations of the beta-carboline norharman. For this purpose, norharman levels in blood plasma were measured up to 90-105 min after both routes of administration. Dose proportionality of three different single oral doses of norharman (7, 65 and 110 microg/kg)
Fekkes, Durk +3 more
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Neurobiology of tetrahydro-β-carbolines
Life Sciences, 1980Abstract Tetrahydro-β-carbolines (THβC's) are tricyclic compounds structurally related to the indoleamines. Recent studies have reported the in vitro and in vivo formation of these compounds in brain and other tissues. This information and other data indicating that THβC's interact relatively specifically with various aspects ...
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ChemInform Abstract: CARBOLINE 1. MITT. 1,4‐DISUBSTITUIERTE BETA‐CARBOLINE
Chemischer Informationsdienst. Organische Chemie, 1970AbstractDie Umsetzung der Oxime (I) mit Phosphorpentachlorid in Nitrobenzol liefert unter Beckmann‐Umlagerung bei 45‐70°C die Dihydrocarboline (II), die sich in wäßriger Lösung in Form ihrer Hydrochloride mit Palladium und Maleinsäure zu den β‐Carbolinen (III) dehydrieren lassen.
K. I. KUCKOVA +2 more
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Discovery and preliminary mechanism of 1-carbamoyl β-carbolines as new antifungal candidates.
European journal of medicinal chemistry, 2021Tao Sheng +7 more
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Photodissociation of β-carboline
Journal of Photochemistry, 1986Abstract An explanation for the photochemical homolytic self-dissociation of β-carboline has been found by means of intermediate neglect of differential overlap (INDO) and complete neglect of differential overlap/spectroscopic parametrization (CNDO/S) molecular orbital calculations.
A. Sánchez-de-Merás +3 more
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Anticancer mechanisms of β‐carbolines
Chemical Biology & Drug DesignAbstractβ‐Carboline nucleus is therapeutically valuable in medicinal chemistry for the treatment of varied number of diseases, most importantly cancer. The potent and wide‐ranging activity of β‐carboline has established them as imperative pharmacological scaffolds especially in the cancer treatment. Numerous derivatives such as Tetrahydro β‐carbolines,
Shivam Mishra +3 more
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