Results 171 to 180 of about 13,653 (252)
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Chromatography of β-carbolines
Journal of Chromatography A, 1967Abstract Chromatography of a series of seventy-three β-carbolines was carried out on both paper and thin-layer plates in acidic, basic, and neutral solvents. The best solvent for the separation is the neutral and polar solvent such as chloroform-methanol on thin-layer chromatography with Silica Gel G.
W M, McIsaac +3 more
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European journal of medicinal chemistry
β-Carbolines, a class of indole-containing heterocyclic alkaloids, are widely distributed in nature and possess diverse bioactivities, making them promising drug candidates against a wide range of diseases.
M. Ur Rehman +6 more
semanticscholar +1 more source
β-Carbolines, a class of indole-containing heterocyclic alkaloids, are widely distributed in nature and possess diverse bioactivities, making them promising drug candidates against a wide range of diseases.
M. Ur Rehman +6 more
semanticscholar +1 more source
Chemico-Biological Interactions, 2019
Alzheimer's disease (AD) is a multifactorial neurodegenerative process whose effective treatment will require drugs that can act simultaneously on multiple pathogenic targets.
G. Makhaeva +7 more
semanticscholar +1 more source
Alzheimer's disease (AD) is a multifactorial neurodegenerative process whose effective treatment will require drugs that can act simultaneously on multiple pathogenic targets.
G. Makhaeva +7 more
semanticscholar +1 more source
An overview on synthetic entries to tetrahydro-β-carbolines
Tetrahedron, 2019The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant biological activities, which promote to develop a plethora of synthetic ...
Pradip Maity +2 more
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Organic Letters, 2019
A metal-free [2 + 2 + 2] cycloaddition of alkyne-cyanamides or ynamide-nitriles with ynamides is described for the efficient synthesis of amino-substituted α- and δ-carbolines.
Jingyi Zhang +5 more
semanticscholar +1 more source
A metal-free [2 + 2 + 2] cycloaddition of alkyne-cyanamides or ynamide-nitriles with ynamides is described for the efficient synthesis of amino-substituted α- and δ-carbolines.
Jingyi Zhang +5 more
semanticscholar +1 more source
Chemistry of Heterocyclic Compounds, 1971
By the direct nitration of harmane and 1,3-dimethyl-, 1-ethyl-, 1-n-propyl-, and 1-isopropyl-β-carbolines with concentrated nitric acid or a mixture of nitric and acetic acids, 6- and 8-nitro-1-alkyl-β-carbolines have been obtained. A chromatographic method for separating the nitration products on alumina is proposed.
A. N. Lomakin, I. V. Terent'eva
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By the direct nitration of harmane and 1,3-dimethyl-, 1-ethyl-, 1-n-propyl-, and 1-isopropyl-β-carbolines with concentrated nitric acid or a mixture of nitric and acetic acids, 6- and 8-nitro-1-alkyl-β-carbolines have been obtained. A chromatographic method for separating the nitration products on alumina is proposed.
A. N. Lomakin, I. V. Terent'eva
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Journal of Organic Chemistry, 2019
A Ru(II)-catalyzed regioselective C-H activation toward hydroxymethylation of β-carbolines and isoquinolines as effective directing groups has been developed, and the mechanism was probed by using online electrospray ionization-tandem mass spectrometry ...
Ramya Tokala +5 more
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A Ru(II)-catalyzed regioselective C-H activation toward hydroxymethylation of β-carbolines and isoquinolines as effective directing groups has been developed, and the mechanism was probed by using online electrospray ionization-tandem mass spectrometry ...
Ramya Tokala +5 more
semanticscholar +1 more source
New 3-tetrazolyl-β-carbolines and β-carboline-3-carboxylates with anti-cancer activity.
European journal of medicinal chemistry, 2019The synthesis and in vitro anticancer activity of novel β-carbolines is reported. New tryptamines have been prepared via hetero-Diels-Alder reaction of nitrosoalkenes with indoles and used to prepare functionalized β-carbolines by the Pictet-Spengler ...
M. R. Panice +7 more
semanticscholar +1 more source
Journal of Organic Chemistry, 2019
Efficient one-pot rhodium-catalyzed and base-mediated transannulation of N-sulfonyl-1,2,3-triazoles with a Michael acceptor-tethered indole derivative have been achieved for the synthesis of dihydro-β-carboline derivatives.
Shanmugam Rajasekar, P. Anbarasan
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Efficient one-pot rhodium-catalyzed and base-mediated transannulation of N-sulfonyl-1,2,3-triazoles with a Michael acceptor-tethered indole derivative have been achieved for the synthesis of dihydro-β-carboline derivatives.
Shanmugam Rajasekar, P. Anbarasan
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Journal of Agricultural and Food Chemistry, 2014
Six known β-carboline, dihydro-β-carboline, and tetrahydro-β-carboline alkaloids and a series of their derivatives were designed, synthesized, and evaluated for their anti-tobacco mosaic virus (TMV) and fungicidal activities for the first time. All of the alkaloids and some of their derivatives (compounds 3, 4, 14, and 19) exhibited higher anti-TMV ...
Hongjian, Song +4 more
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Six known β-carboline, dihydro-β-carboline, and tetrahydro-β-carboline alkaloids and a series of their derivatives were designed, synthesized, and evaluated for their anti-tobacco mosaic virus (TMV) and fungicidal activities for the first time. All of the alkaloids and some of their derivatives (compounds 3, 4, 14, and 19) exhibited higher anti-TMV ...
Hongjian, Song +4 more
openaire +2 more sources